222410-08-4

Upstream product

• 222410-03-9 N-tert-butyl-3-(hydroxymethyl)benzenesulfonamide 
• 222409-98-5 3-(tert-butylsulfamoyl)benzoic acid 
• 4025-64-3 3-Carboxybenzenesulfonyl chloride 

Downstream Products

• 222410-29-9 ethyl (2S,3S)-3-(Boc-amino)-3-<3-(tert-butylsulfamoyl)phenyl>-2-<(4-methoxybenzyl)sulfanyl>propanoate 
• 224822-78-0 (2SR,3S)-3-(Boc-amino)-3-<3-(tert-butylsulfamoyl)phenyl>-2-<(4-methoxybenzyl)sulfanyl>propanoic acid 
• 222410-26-6 ethyl (3R)-3-(Boc-amino)-3-<3-(tert-butylsulfamoyl)phenyl>propanoate 
• 222410-28-8 ethyl (3S)-3-(Boc-amino)-3-<3-(tert-butylsulfamoyl)phenyl>propanoate 

Relevant academic research and scientific papers

NOVEL IMIDAZOLE COMPOUND AND USE THEREOF AS MELANOCORTIN RECEPTOR AGONIST

The present invention relates to a novel imidazole compound or a pharmaceutically acceptable salt thereof having a melanocortin receptor agonistic activity, and medical use thereof. The present invention relates to an imidazole compound represented by general formula [I] [wherein: Ring A represents an optionally substituted aryl group or the like; R1 represents a hydrogen atom, an optionally substituted alkyl group, or the like; R2 represents a hydrogen atom, a halogen atom, or the like; and R3 represents an optionally substituted alkyl group] or a pharmaceutically acceptable salt thereof.

Pharmaceutical compositions (by machine translation)

[Problem] imidazole compound or its pharmacologically acceptable salt in the melanocortin receptor activity that operates as an active ingredient of a pharmaceutical composition comprising. "I" general formula [a]" Formula, the aryl group may be substituted A ring represents a; R1 Represents a hydrogen atom, or an alkyl group which may be substituted represented; R2 Represents a hydrogen atom, a halogen atom or represents a; R3 The alkyl group may be substituted " represented by the imidazole compound, its pharmacologically acceptable salt as an active ingredient in a pharmaceutical composition. [Drawing] no (by machine translation)

Phenylglycinamide and pyridylglycinamide derivatives useful as anticoagulants

The present invention provides novel phenylglycinamide derivatives of Formula (I) or (IV): or a stereoisomer, tautomer, pharmaceutically acceptable salt, solvate, or prodrug thereof, wherein the variables W, W1, Y, Z, R7, R8, R9, and R11 are as defined herein. These compounds are selective inhibitors of factor VIIa which can be used as medicaments.

Metallopeptidase inhibitors of tetanus toxin: A combinatorial approach

The bacterial protein tetanus toxin (TeNt), which belongs to the family of zinc endopeptidases, cleaves synaptobrevin, an essential synaptic protein component of the neurotransmitter exocytosis apparatus, at a single peptide bond (Gln76-Phesup