ATORVASTATIN-D5, SODIUM SALT is a deuterated selective, competitive HMG-CoA reductase inhibitor. It is a light tan solid and is the only drug in its class specifically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.
222412-87-5
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Basic information
- Product Name: ATORVASTATIN-D5, SODIUM SALT
- Synonyms: ATORVASTATIN-D5, SODIUM SALT;LIPITOR-D5, SODIUM SALT;(R,dR)-2-(4-Fluorophenyl)-,d-dihydroxy-5-(1-methylethyl)-3-(phenyl-d5)-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid Sodium;3S,5S-Atorvastatin-d5 Sodium;Lipitor-d5 Sodium;(βR,δR)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1-Methylethyl)-3-(phenyl-d5)-4-[(phenylaMino)carbonyl]-1H-pyrrole-1-heptanoic Acid SodiuM
- CAS NO:222412-87-5
- Molecular Formula: C33H29D5FN2NaO5
- Molecular Weight: 585.65
- EINECS: N/A
- Product Categories: Inhibitors;Intermediates & Fine Chemicals;Isotope Labeled Compounds;Pharmaceuticals;Inhibitores;Chiral Reagents;Isotope Labelled Compounds
- Mol File: 222412-87-5.mol
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Chemical Properties
- Melting Point: 228-230°C
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: -20°C Freezer
- Solubility: DMSO (Slightly), Methanol (Slightly), Water (Slightly)
- Stability: Hygroscopic
- CAS DataBase Reference: ATORVASTATIN-D5, SODIUM SALT(CAS DataBase Reference)
- NIST Chemistry Reference: ATORVASTATIN-D5, SODIUM SALT(222412-87-5)
- EPA Substance Registry System: ATORVASTATIN-D5, SODIUM SALT(222412-87-5)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 222412-87-5(Hazardous Substances Data)
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222412-87-5 Usage
Uses
Used in Pharmaceutical Industry:ATORVASTATIN-D5, SODIUM SALT is used as a cholesterol-lowering agent for the treatment of hypercholesterolemia. It works by inhibiting the enzyme HMG-CoA reductase, which is responsible for the production of cholesterol in the liver. This helps to reduce the levels of low-density lipoprotein (LDL) cholesterol and triglycerides in the blood, thereby decreasing the risk of cardiovascular diseases.
ATORVASTATIN-D5, SODIUM SALT is also used as a research compound in the development of new drugs and therapies for the treatment of hypercholesterolemia and related conditions. Its deuterated nature allows for the study of its effects and mechanisms of action in a more controlled and precise manner.
Check Digit Verification of cas no
The CAS Registry Mumber 222412-87-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,2,4,1 and 2 respectively; the second part has 2 digits, 8 and 7 respectively.Calculate Digit Verification of CAS Registry Number 222412-87:
(8*2)+(7*2)+(6*2)+(5*4)+(4*1)+(3*2)+(2*8)+(1*7)=95
95 % 10 = 5
So 222412-87-5 is a valid CAS Registry Number.
222412-87-5Upstream product
222412-87-5Downstream Products
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ATORVASTATIN-D5, SODIUM SALT
