222419-17-2

Upstream product

• 222419-07-0 (3S,5R)-5-Benzyloxymethyl-3-phenylselanyl-dihydro-furan-2-one 
• 222419-10-5 (3R,5R)-5-Benzyloxymethyl-3-phenylselanyl-dihydro-furan-2-one 
• 77697-15-5 (R)-(-)-γ-benzyloxymethyl-γ-butyrolactone 
• 34837-55-3 Phenylselenyl bromide 
• 222419-16-1 5-((1R,2S,4R)-5-Benzyloxy-1,4-dihydroxy-2-phenylselanyl-pentyl)-2-(tert-butyl-dimethyl-silanyl)-imidazole-1-sulfonic acid dimethylamide 
• 222419-19-4 5-((1S,2R,4R)-5-Benzyloxy-1,4-dihydroxy-2-phenylselanyl-pentyl)-2-(tert-butyl-dimethyl-silanyl)-imidazole-1-sulfonic acid dimethylamide 
• 222419-29-6 5-((1S,2S,4R)-5-Benzyloxy-1,4-dihydroxy-2-phenylselanyl-pentyl)-2-(tert-butyl-dimethyl-silanyl)-imidazole-1-sulfonic acid dimethylamide 

Relevant academic research and scientific papers

Synthesis of imifuramine and its stereoisomers exhibiting histamine H3- agonistic activity

The four possible stereoisomers of a novel imidazole C-nucleoside derivative were synthesized by the efficient use of a PhSe group. Among them, (+)-4(5)-[(2R, SR)-5-(aminomethyl)tetrahydrofuran-2-yl]imidazole (imifuramine) was indicated as a novel type of histamine H3-agonist by a brain microdialysis method.