222420-78-2

Upstream product

• 1623-08-1 phosphoric acid dibenzyl ester 
• 80582-74-7 (1S,2S,3S,4S)-anti-benzene dioxide 

Downstream Products

• 74465-19-3 D-myo-Inositol 1,4-bisphosphate 
• 281206-70-0 5,6-di-O-acetyl-1,4-bis-O-(di-O-benzylphospho)-2,3-bis-O-(3-oxo-1,5-dihydro-3λ⁵-2,4,3-benzodioxaphosphepin-3-yl)-D-myo-inositol 
• 281206-69-7 5,6-di-O-acetyl-1,4-bis-O-(di-O-benzylphospho)-D-myo-inositol 
• 281206-68-6 (1R,2S,3S,4R)-2,3-di-O-acetyl-1,4-bis-O-(di-O-benzylphospho)conduritol B 

Relevant academic research and scientific papers

De novo synthesis of the enantiomers Ins(1,2,3,4)P4 and Ins(1,2,3,6)P4-regiospecificity of their enzymatic dephosphorylation

The first total synthesis of Ins(1,2,3,4)P4 and Ins(1,2,3,6)P4 is presented. Starting from p-benzoquinone, we took advantage of the C2-symmetry of conduritol-B intermediates. The target compounds were dephosphorylated by s

Enzyme-assisted total synthesis of the optical antipodes D-myo-inositol 3,4,5-trisphosphate and D-myo-inositol 1,5,6-trisphosphate: Aspects of their structure-activity relationship to biologically active inositol phosphates

Unambiguous total syntheses of both optical antipodes of the enantiomeric pair D-myo-inositol 3,4,5-trisphosphate (Ins(3,4,5)P3) and D- myo-inositol 1,5,6-trisphosphate (Ins(1,5,6)P3) are described. The ring system characteristic of