222532-16-3

Downstream Products

• 222532-30-1 6-(Heptafluoropropyl)-9-(2,3-O-isopropylidene-5-O-trityl-β-D-ribofuranosyl)purine 
• 1023754-54-2 9-{2,2-dimethyl-6-[(trityloxy)methyl]tetrahydrofuro[3,4-d] [1,3]dioxol-4-yl}-6-(4-methylpiperazin-1-yl)-9H-purine 
• 1258274-90-6 7-benzyl-7,8-dihydro-6-iodo-9-(2,3-O-isopropylidene-5-O-trityl-β-D-ribofuranosyl)purine 
• 222532-19-6 9-(2,3-O-Isopropylidene-5-O-trityl-β-D-ribofuranosyl)-6-(trifluoromethyl)purine 

Relevant academic research and scientific papers

Perfluoroalkylation of 6-iodopurines by trimethyl(perfluoroalkyl)silanes. Synthesis of 6-(perfluoroalkyl)purine bases, nucleosides and acyclic nucleotide analogues

A Cul/KF mediated perfluoroalkylation reaction of various 9-substituted 6-iodopurines 1 with trimethyl(trifluoromethyl)silane or heptafluoropropyl(trimethyl)silane was used for the synthesis of the corresponding 6-(trifluoromethyl)-and 6-(heptafluoropropy