222550-60-9 Usage
Uses
Used in Pharmaceutical Synthesis:
(S)-N-Ethylalanine methyl ester is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the formation of complex molecular structures with specific biological activities.
Used as a Chiral Auxiliary in Asymmetric Synthesis:
In the field of asymmetric synthesis, (S)-N-Ethylalanine methyl ester is utilized as a chiral auxiliary to facilitate the production of enantiomerically pure compounds, which is crucial for the development of drugs with targeted therapeutic effects and reduced side effects.
Used in Organic Synthesis as a Building Block:
(S)-N-Ethylalanine methyl ester serves as a versatile building block in organic synthesis, enabling the creation of a wide range of organic compounds with potential applications in various industries, including materials science, agrochemicals, and specialty chemicals.
Used in Drug Development:
(S)-N-Ethylalanine methyl ester has potential applications in the development of new drugs, where its unique structural features can be leveraged to design molecules with novel mechanisms of action or improved pharmacokinetic properties.
It is important to handle (S)-N-Ethylalanine methyl ester with care due to its potential hazards to human health and the environment, ensuring safe practices in its synthesis and application.
Check Digit Verification of cas no
The CAS Registry Mumber 222550-60-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,2,5,5 and 0 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 222550-60:
(8*2)+(7*2)+(6*2)+(5*5)+(4*5)+(3*0)+(2*6)+(1*0)=99
99 % 10 = 9
So 222550-60-9 is a valid CAS Registry Number.
222550-60-9Relevant academic research and scientific papers
N-(4-nitrophenylsulfonyl)- And N-(fluorenylmethoxycarbonyl)-N-ethyl amino acid methyl esters - A practical approach
Belsito, Emilia Lucia,De Marco, Rosaria,Di Gioia, Maria Luisa,Liguori, Angelo,Perri, Francesca,Viscomi, Maria Caterina
experimental part, p. 4245 - 4252 (2010/09/20)
An efficient one-pot preparation of N-ethyl-N-4-nitrophenylsulfonyl (nosyl) amino acid methyl esters was accomplished by a simple N-ethylation reaction by using triethyloxonium tetrafluoroborate in the presence of N,N- diisopropylethylamine, The N-ethylated amino acid methyl esters are obtained with total retention of stereochemistry at the original chiral centers. To further broaden the scope of this methodology, the N-ethylated nosyl-protected compounds are easily converted in the more practical fluorenylmethyloxycarbonyl (Fmoc)-protected derivatives. The cleavage of methyl ester by using a mild and neutral method enables the preparation of N-ethyl amino acids that are building blocks suitable for introduction into a peptide chain. The methodology works well with both nosyl- and Fmoc-based solution-phase peptide synthesis.
