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Curarine, also known as tubocurarine, is a naturally occurring alkaloid derived from the South American vine Chondrodendron tomentosum and other plant species. It is a potent neurotoxin that exerts its effects by blocking acetylcholine receptors at the neuromuscular junction, resulting in muscle paralysis. Curarine has a long history of use as a poison for hunting and warfare by indigenous tribes in South America. In contemporary medicine, it has been repurposed as a muscle relaxant for surgical procedures and the treatment of muscle spasms. Due to its inherent toxicity, curarine must be administered with caution and under the supervision of trained medical professionals.

22260-42-0

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22260-42-0 Usage

Uses

Used in Surgical Procedures:
Curarine is used as a muscle relaxant during surgical operations to facilitate the process by inducing muscle paralysis. This allows surgeons to perform delicate procedures with greater ease and precision, as the patient's muscles remain still throughout the operation.
Used in Treatment of Muscle Spasms:
Curarine is employed as a therapeutic agent for the treatment of muscle spasms, where it helps to alleviate the involuntary contractions and pain associated with these conditions. By blocking acetylcholine receptors, curarine effectively reduces the intensity and frequency of muscle spasms, providing relief to affected individuals.
Used in Research:
Curarine is also utilized in scientific research as a tool to study the function and mechanisms of the neuromuscular junction. Its ability to block acetylcholine receptors makes it a valuable compound for investigating the role of these receptors in muscle contraction and neurotransmission.
Used in Toxicological Studies:
Due to its potent neurotoxin properties, curarine is used in toxicological research to better understand the effects of toxins on the nervous system and to develop potential antidotes or treatments for poisoning.

Check Digit Verification of cas no

The CAS Registry Mumber 22260-42-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,2,6 and 0 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 22260-42:
(7*2)+(6*2)+(5*2)+(4*6)+(3*0)+(2*4)+(1*2)=70
70 % 10 = 0
So 22260-42-0 is a valid CAS Registry Number.

22260-42-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name Curarine

1.2 Other means of identification

Product number -
Other names Tubocurarin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:22260-42-0 SDS

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