222610-57-3Relevant articles and documents
Structure-activity relationship of diaryl phosphonate esters as potent irreversible dipeptidyl peptidase IV inhibitors.
Belayev, Alexander,Zhang, Xuemei,Augustyns, Koen,Lambeir, Anne-Marie,Meester, Ingrid De,et al.
, p. 1041 - 1052 (2007/10/03)
The previously reported diphenyl 1-(S)-prolylpyrrolidine-2(R, S)-phosphonate (5) was used as a lead compound for the development of potent and irreversible inhibitors of dipeptidyl peptidase IV (DPP IV, EC 3.4.14.5). The synthesis of a series of diaryl 1-