222633-66-1

Basic information

• Product Name: methyl 4-(3,4-dimethoxyphenyl)-4-oxobut-2-ynoate
• Synonyms: methyl 4-(3,4-dimethoxyphenyl)-4-oxobut-2-ynoate
• CAS NO: 222633-66-1
• Molecular Weight: 248.235
• Mol File: 222633-66-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 4-(3,4-dimethoxyphenyl)-4-oxobut-2-ynoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-(3,4-dimethoxyphenyl)-4-oxobut-2-ynoate(222633-66-1)
• EPA Substance Registry System: methyl 4-(3,4-dimethoxyphenyl)-4-oxobut-2-ynoate(222633-66-1)

Safety Data

• Hazardous Substances Data: 222633-66-1(Hazardous Substances Data)

Upstream product

• 120-14-9 3,4-dimethoxy-benzaldehyde 

Downstream Products

• 101597-68-6 methyl 2-(3,4-dimethoxybenzoyl)benzoate 
• 22506-55-4 2,3-dimethoxy-anthraquinone 

Relevant articles and documents

Synthesis of fluorenone and anthraquinone derivatives from aryl- and aroyl-substituted propiolates

Fluorenone derivatives were generated from aryl-substituted propiolates via a cobalt-catalyzed Diels-Alder reaction/DDQ-oxidation and Friedel-Crafts-type cyclization. Several functional groups are tolerated, and good to excellent overall yields (up to 89%) could be achieved. For the synthesis of anthraquinone derivatives, aroyl-substituted propiolates were applied in a zinc iodide catalyzed Diels-Alder reaction with 1,3-dienes. The subsequent DDQ oxidation and Friedel-Crafts-type cyclization led to symmetrical as well as some unsymmetrical anthraquinones in good to excellent yields of up to 87% over the three-step reaction sequence.