22276-97-7 Usage
Uses
Used in Pharmaceutical Synthesis:
7-bromo-2,4,9-triazabicyclo[4.3.0]nona-3,7,10-trien-5-one is utilized as a key intermediate in the synthesis of various pharmaceuticals due to its unique structure and reactivity. Its presence in the molecular framework of target compounds can potentially enhance their therapeutic properties and efficacy.
Used in Medicinal Chemistry Research:
In the realm of medicinal chemistry, 7-bromo-2,4,9-triazabicyclo[4.3.0]nona-3,7,10-trien-5-one is employed as a valuable component in the design and development of new drugs. Its incorporation into drug candidates can lead to the discovery of novel therapeutic agents with improved pharmacological profiles.
Used in Drug Discovery:
7-bromo-2,4,9-triazabicyclo[4.3.0]nona-3,7,10-trien-5-one is also used in drug discovery processes to identify and optimize biologically active molecules. Its unique structural features can contribute to the creation of new chemical entities with potential applications in treating various diseases and medical conditions.
Used in Organic Chemistry:
7-bromo-2,4,9-triazabicyclo[4.3.0]nona-3,7,10-trien-5-one serves as a versatile building block in organic chemistry, enabling the synthesis of a wide range of organic compounds with diverse applications. Its reactivity and structural attributes make it a useful tool for organic chemists in the development of new synthetic routes and methodologies.
Check Digit Verification of cas no
The CAS Registry Mumber 22276-97-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,2,7 and 6 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 22276-97:
(7*2)+(6*2)+(5*2)+(4*7)+(3*6)+(2*9)+(1*7)=107
107 % 10 = 7
So 22276-97-7 is a valid CAS Registry Number.
InChI:InChI=1/C6H4BrN3O/c7-3-1-8-5-4(3)6(11)10-2-9-5/h1-2H,(H2,8,9,10,11)
22276-97-7Relevant academic research and scientific papers
HETEROAROMATIC NMDA RECEPTOR MODULATORS AND USES THEREOF
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Paragraph 00156, (2017/07/27)
Disclosed herein, in part, are heteroaromatic compounds and methods of use in treating neuropsychiatric disorders, e.g., schizophrenia and major depressive disorder. Pharmaceutical compositions and methods of making heteroaromatic compounds are provided. The compounds are contemplated modulate the NMDA receptor.
A Convenient Method for Regioselective C-5 Halogenation of 4(3H)-Oxo-7H-pyrrolopyrimidines
Barnett, Charles J.,Kobierski, Michael E.
, p. 1181 - 1184 (2007/10/02)
N-7, O-Disilylation of 4(3H)-oxo-7H-pyrrolopyrimidines provides a convenient method for activation of these compounds toward regiospecific halogenation at C-5.The sequence is conveniently carried out without isolation of the silylated derivatives and desilylation is spontaneous upon addition of water to the reaction mixture.
Process for the synthesis of 4-hydroxy-5-halopyrrold[2,3-d]pyrimidine intermediates
-
, (2008/06/13)
4-Hydroxypyrrolo[2,3-d]pyrimidines are regiospecifically halogenated at the C-5 position by silylation in the presence of an inert organic solvent and iodination, bromination or chlorination.
