222834-28-8Relevant articles and documents
(-)3-[4-[2-(phenoxazin-10-yl)ethoxy]phenyl]-2-ethoxypropanoic acid [(-)DRF 2725]: A dual PPAR agonist with potent antihyperglycemic and lipid modulating activity
Lohray,Lohray,Bajji,Kalchar,Poondra,Padakanti,Chakrabarti,Vikramadithyan,Misra,Juluri,Mamidi,Rajagopalan
, p. 2675 - 2678 (2007/10/03)
(-)DRF 2725 (6) is a phenoxazine analogue of phenyl propanoic acid. Compound 6 showed interesting dual activation of PPARα and PPARγ. In insulin resistant db/db mice, 6 showed better reduction of plasma glucose and triglyceride levels as compared to rosig