222840-73-5 Usage
General Description
3-Hydroxymethylthiophene-2-boronic acid is a chemical compound with the molecular formula C5H7BO3S. It is a boronic acid derivative with a thiophene ring attached to a boron atom and a hydroxymethyl group. 3-HYDROXYMETHYLTHIOPHENE-2-BORONIC ACID is used in organic synthesis as a reagent for cross-coupling reactions and as a building block in the production of pharmaceuticals, agrochemicals, and materials science. It is also used in the development of sensors and electronic devices due to its unique electronic and chemical properties. Additionally, 3-Hydroxymethylthiophene-2-boronic acid has potential applications in the field of medicinal chemistry and drug discovery due to its ability to interact with biological molecules and enzymes.
Check Digit Verification of cas no
The CAS Registry Mumber 222840-73-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,2,8,4 and 0 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 222840-73:
(8*2)+(7*2)+(6*2)+(5*8)+(4*4)+(3*0)+(2*7)+(1*3)=115
115 % 10 = 5
So 222840-73-5 is a valid CAS Registry Number.
222840-73-5Relevant articles and documents
The discovery of 4-{l-[({2,5-dimethyl-4-[4-(trifluoromethyl)benzyl]- 3thienyl}carbonyl)amino]cyclopropyl}benzoic acid (MK-2894), a potent and selective prostaglandin e2 subtype 4 receptor antagonist
Blouin, Marc,Han, Yongxin,Burch, Jason,Farand, Julie,Mellon, Christophe,Gaudreault, Mireille,Wrona, Mark,Lévesque, Jean-Fran?ois,Denis, Danielle,Mathieu, Marie-Claude,Stocco, Rino,Vigneault, Erika,Therien, Alex,Clark, Patsy,Rowland, Steve,Xu, Daigen,o'Neill, Gary,Ducharme, Yves,Friesen, Rick
supporting information; experimental part, p. 2227 - 2238 (2010/08/21)
The discovery of highly potent and selective second generation EP4 antagonist MK-2894 (34d) is discussed. This compound exhibits favorable pharmacokinetic profile in a number of preclinical species and potent anti-inflammatory activity in several animal models of pain/inflammation. It also shows favorable GI tolerability profile in rats when compared to traditional NSAID indomethacin.
