222840-73-5 Usage
Uses
Used in Organic Synthesis:
3-Hydroxymethylthiophene-2-boronic acid is utilized as a reagent in cross-coupling reactions, a key technique in organic synthesis for forming carbon-carbon bonds. Its role in these reactions is crucial for the construction of complex organic molecules.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 3-Hydroxymethylthiophene-2-boronic acid serves as a building block for the synthesis of various drugs. Its ability to be incorporated into the molecular structures of potential medications makes it a valuable component in drug discovery and development.
Used in Agrochemical Development:
3-HYDROXYMETHYLTHIOPHENE-2-BORONIC ACID also finds application in the agrochemical sector, where it is used in the synthesis of pesticides and other agricultural chemicals. Its role in these applications is to contribute to the creation of effective and targeted agrochemicals.
Used in Materials Science:
3-Hydroxymethylthiophene-2-boronic acid is employed in materials science for the development of new materials with specific properties. Its unique characteristics allow it to be a part of innovative material compositions.
Used in Sensor and Electronic Device Development:
Due to its electronic properties, 3-Hydroxymethylthiophene-2-boronic acid is used in the development of sensors and electronic devices. Its integration into these technologies can enhance their performance and sensitivity.
Used in Medicinal Chemistry and Drug Discovery:
3-Hydroxymethylthiophene-2-boronic acid has potential applications in medicinal chemistry, where it can interact with biological molecules and enzymes. This interaction is vital for the exploration of new drug targets and the advancement of treatment options.
Check Digit Verification of cas no
The CAS Registry Mumber 222840-73-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,2,8,4 and 0 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 222840-73:
(8*2)+(7*2)+(6*2)+(5*8)+(4*4)+(3*0)+(2*7)+(1*3)=115
115 % 10 = 5
So 222840-73-5 is a valid CAS Registry Number.
222840-73-5Relevant academic research and scientific papers
The discovery of 4-{l-[({2,5-dimethyl-4-[4-(trifluoromethyl)benzyl]- 3thienyl}carbonyl)amino]cyclopropyl}benzoic acid (MK-2894), a potent and selective prostaglandin e2 subtype 4 receptor antagonist
Blouin, Marc,Han, Yongxin,Burch, Jason,Farand, Julie,Mellon, Christophe,Gaudreault, Mireille,Wrona, Mark,Lévesque, Jean-Fran?ois,Denis, Danielle,Mathieu, Marie-Claude,Stocco, Rino,Vigneault, Erika,Therien, Alex,Clark, Patsy,Rowland, Steve,Xu, Daigen,o'Neill, Gary,Ducharme, Yves,Friesen, Rick
supporting information; experimental part, p. 2227 - 2238 (2010/08/21)
The discovery of highly potent and selective second generation EP4 antagonist MK-2894 (34d) is discussed. This compound exhibits favorable pharmacokinetic profile in a number of preclinical species and potent anti-inflammatory activity in several animal models of pain/inflammation. It also shows favorable GI tolerability profile in rats when compared to traditional NSAID indomethacin.
