22298-82-4Relevant academic research and scientific papers
Reaction of Acetone with 2-Ketotetrahydroquinoxaline under Free Radical Conditions: An Easy Synthesis of 3-(2-Oxopropyl)-2(1H)-quinoxalinone
Goswami, M.,Borthakur, N.
, p. 525 - 526 (2007/10/02)
Acetone under free radical conditions reacts with 2-ketotetrahydroquinoxaline (1) to produce 3-(2-oxopropyl)-2(1H)-quinoxalinone (6) and 2-hydroxyquinoxaline (4), probably through a common intermediate 2 in nitrogen atmosphere.However in the presence of air 2 is converted into another red coloured intermediate (3) which in turn changes to 4.Reaction of 1 with ethyl methyl ketone and acetophenone produces 3-(2-oxobutyl)-2(1H)-quinoxalinone 7 and 3-(2-oxo-2-phenylethyl)-2(1H)-quinoxalinone (8) respectively.
