223-47-2

Upstream product

• 55969-61-4 1-(Benzothiophen-3-yl)-2-(2'-naphthyl)ethene 
• 5381-23-7 2-bromo-3-methylbenzothiophene 
• 183861-05-4 2-bromo-3-(bromomethyl)benzo[b]thiophene 
• 1455-18-1 3-methylbenzothiophene 
• 5392-10-9 2-bromo-4,5-dimethoxybenzaldehyde 

Relevant academic research and scientific papers

Synthetic Utility of Arylmethylsulfones: Annulative π-Extension of Aromatics and Hetero-aromatics Involving Pd(0)-Catalyzed Heck Coupling Reactions

A straightforward and general method for the synthesis of annulated thiophene, dibenzothiophene, and carbazoles analogues has been achieved involving alkylation of 2-bromo-1-(phenylsulfonylmethyl)arene/heteroarene with arylmethyl bromides/heteroarylmethyl bromides using t-BuOK as a base in DMF, followed by Pd(0)-mediated intramolecular Heck coupling in the presence of K2CO3 in DMF at 80-140 °C. The attractive feature of this protocol is that a wide variety of π-conjugated heterocycles could be readily accessed by an appropriate choice of arylmethylsulfones and benzylic bromides.

Synthesis of Benzophenanthrothiophenes

The synthesis of benzophenanthrothiophene (1), benzophenanthrothiophene (2), benzophenanthrothiophene (3) and benzophenanthrothiophene (4) from appropriately substituted olefines by photochemical cyclodehydration is described.The photolysis of olefin 9 gave a mixture of 4 and anthrabenzothiophene (5).