22318-80-5

Usage

InChI:InChI=1/C14H14O4/c15-11-5-10(6-12(16)8-11)2-1-9-3-4-13(17)14(18)7-9/h3-8,15-18H,1-2H2

Upstream product

• 10083-24-6 trans-piceatannol 
• 4339-71-3 piceatannol 
• 22268-21-9 3,4,3',5'-Tetraacetoxy-dibenzyl 
• 20578-93-2 3,4,3',5'-tetraacetoxy-stilbene 
• 139-85-5 3,4-dihydroxybenzaldehyde 
• 22318-87-2 3,5,4',5'-tetramethoxydihydrostilbene 
• 20767-18-4 cis-trans-3,3',4',5-tetramethoxystilbene 
• 24131-30-4 (3,5-dimethoxybenzyl)triphenylphosphonium bromide 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 62502-05-0 3'-β-D-Glucopyranosyloxy-3,4,5'-trihydroxy-1,2-diphenylethane 

Relevant academic research and scientific papers

Biologically active constituents of Melaleuca leucadendron: Inhibitors of induced histamine release from rat mast cells

Chloroform and methanol extracts of the fruits of Melaleuca leucadendron strongly inhibited histamine release from rat mast cells induced by compound 48/80 or concanavalin A. Ursolic acid, a triterpene, was the most active compound contained in the chloro

Synthetic method for piceatannol derivatives and pharmaceutical compounds containing the piceatannol derivatives

The piceatannol derivatives were easily synthesized using a Wittig-Horner reaction, a Colvin rearrangement and a Sonogashira reaction. According to the result of investigating the anti-inflammatory activity of compounds synthesized in RAW264.7 macrophages induced by LPS, compounds 6 to 8 showed remarkable activity at the concentration of 10 andmu;M, and a compound 7 (90.1%), a compound 8 (60.8%) and a compound 6 (55.2%) showed no cytotoxicity. The present invention aims to provide a method for efficiently synthesizing the piceatannol derivatives and to confirm the biological activity of synthesized piceatannol derivatives.COPYRIGHT KIPO 2017

Prevention of Marine Biofouling Using the Natural Allelopathic Compound Batatasin-III and Synthetic Analogues

The current study reports the first comprehensive evaluation of a class of allelopathic terrestrial natural products as antifoulants in a marine setting. To investigate the antifouling potential of the natural dihydrostilbene scaffold, a library of 22 syn

Identification of dihydrostilbenes in Pholidota chinensis as a new scaffold for GABAA receptor modulators

A dichloromethane extract of stems and roots of Pholidota chinensis (Orchidaceae) enhanced GABA-induced chloride currents (IGABA) by 132.75 ± 36.69% when tested at 100 μg/mL in a two-microelectrode voltage clamp assay, on Xenopus laevis oocytes

Antioxidant constituents from rhubarb: Structural requirements of stilbenes for the activity and structures of two new anthraquinone glucosides

The methanolic extracts from five kinds of rhubarb were found to show scavenging activity for DPPH radical and ·O2-. Two new anthraquinone glucosides were isolated from the rhizome of Rheum undulatum L. together with two anthraquinone glucosides, a naphthalene glucoside, and 10 stilbenes. In the screening test for radical scavenging activity of rhubarb constituents, stilbenes and a naphthalene glucoside showed activity, but anthraquinones and sennosides did not. In addition, most stilbenes inhibited lipid peroxidation of erythrocyte membrane by tert-butyl hydroperoxide. Detailed examination of the scavenging effect on various related compounds suggested the following structural requirements; 1) phenolic hydroxyl groups are essential to show the activity; 2) galloyl moiety enhances the activity; 3) glucoside moiety reduces the activity; 4) dihydrostilbene derivatives maintain the scavenging activity for the DPPH radical, but they show weak activity for ·O2-. In addition, several stilbenes with both the 3-hydroxyl and 4′-methoxyl groups inhibited xanthine oxidase.

ANTI-LEUKAEMIC COMPOUNDS DERIVED FROM STILBENES IN PICEA ABIES BARK

Resveratrol was identified and isolated as a minor stilbene derivative from the bark of Picea abies.Three derivatives of resveratrol and three additional derivatives of primary stilbenes from P. abies bark were prepared.Improvement over piceatannol in ant