22326-31-4

Usage

Uses

Used in Polymer Synthesis:
5-Sulfoisophthalic acid is used as a building block for the synthesis of various polymers, particularly sulfonated polyesters. Its strong acidic properties and sulfonic acid group contribute to the formation of polymers with unique properties, such as enhanced solubility and reactivity.
Used as a Catalyst in Organic Synthesis:
5-Sulfoisophthalic acid is used as a catalyst in the synthesis of various organic compounds. Its strong acidity facilitates the acceleration of certain chemical reactions, making it a valuable component in the production of a wide range of organic compounds.
Used in the Production of Polyethylene Terephthalate (PET) and Other Polyester Polymers:
5-Sulfoisophthalic acid is used as a stabilizer in the production of polyethylene terephthalate (PET) and other polyester polymers. Its strong acidic properties help to improve the stability and performance of these polymers, making them suitable for various applications, such as packaging materials and textiles.

InChI:InChI=1/C8H6O7S/c9-7(10)4-1-5(8(11)12)3-6(2-4)16(13,14)15/h1-3H,(H,9,10)(H,11,12)(H,13,14,15)

Upstream product

• 121-91-5 isophthalic acid 
• 148065-78-5 5,5'-Dithiodiisophthalic acid 

Relevant academic research and scientific papers

SALTS OF 5-SULFOISOPHTHALIC ACID AND METHOD OF MAKING SAME

This invention relates to methods for the production of various metal salts of 5-sulfoisophthalic acid including those where the metal cation is selected from the group consisting of silver (I), sodium, potassium, rubidium, cesium, magnesium, calcium, strontium, barium, manganese (II), iron (II), cobalt (II), nickel (II), copper (I), copper (II), zinc, yttrium, and cadmium. The methods utilize a solvent system that comprises acetic acid or water or a mixture of both. The invention also encompasses the various metal salts of 5-sulfoisophthalic acid.

USE OF AN ACETIC ACID WASH TO PREPARE LOW-SULFATE 5-SULFOISOPHTHALIC ACID, MONO-LITHIUM SALT

There is disclosed a process for making a mono-lithium salt of 5-sulfoisophthalic acid (LiSIPA) having less than 500 ppm sulfate. The process uses a reaction mixture of water, a lithium cation producing compound, and 5-sulfoisophthalic acid. The reaction mixture is heated to reflux, cooled, filtered and washed with acetic acid to obtain a high quality LiSIPA having less than 500 ppm sulfate. Also disclosed is a high quality, non-purified reaction product containing a mono-lithium salt of 5-sulfoisophthalic acid and having less than 500 ppm sulfate.

DIAMINIUM BIS-3,5-DICARBOXYBENZENSULFONATE AND TRI-DIAMINIUM BIS-3,5-DICARBOXYBENZENSULFONATE AND METHODS FOR PRODUCING SAME

A composition of matter comprising a diamine salt and sulfoisophthalic acid in a ratio other than one salt to one acid and a process for producing a diamine salt of sulfoisophthalic acid comprising generating a sulfoisophthalic acid and charging the sulfoisophthalic acid with diamine.

Naaladase inhibitors for treating retinal disorders and glaucoma

The present invention relates to pharmaceutical compositions and methods for treating a retinal disorder or glaucoma using NAALADase inhibitors.

Naaladase inhibitors for treating amyotrophic lateral sclerosis

The present invention relates to pharmaceutical compositions and methods for treating amyotrophic lateral sclerosis using NAALADase inhibitors.

Benzenedicarboxylic acid derivatives

New benzenedicarboxylic acid derivative compounds; pharmaceutical compositions, diagnostic methods, and diagnstic kits that include those compounds; and methods of using those compounds for inhibiting NAALADase enzyme activity, detecting diseases where NAALADase levels are altered, effecting neuronal activity, effecting TGF-β activity, inhibiting angiogenesis, and treating glutamate abnormalities, neutopathy, pain, compulsive disorders, prostate diseases, cancers, and glaucoma.

THE AQUEOUS PERIODATE OXIDATION OF AROMATIC AND ALIPHATIC CARBOXYLIC ACID DISULFIDES

The water-soluble carboxylic acid-functionalized aromatic disulfides, 3,3'-dithiodibenzoic acid and 5,5'-dithiodiisophthalic acid (5,5'-dithiodi(1,3-benzenedicarboxylic acid)) were prepared and their rates of periodate oxidation to the sulfonic acids were determined.The reaction is first order in each of the reactants which indicates that the slow step is the initial oxidative cleavage step.These aromatic disulfides are oxidized to the sulfonic acids 4-8 times more slowly than a typical aliphatic disulfide.In all cases, water solubility of the disulfide is of prime importance.The periodate oxidation of two aliphatic carboxylic acid analogs were also examined, however, in these cases, the reactions were multiphasic and intermediate thiosulfinates were observed by 1H NMR along with the sulfonic acids.Key words: Periodate; disulfide; thiosulfonate; sulfonic acid, carboxylic acid, ABTS.