22327-82-8

Usage

Uses

Used in Pharmaceutical Research and Development:
2β,3β,16α,23,24-Pentahydroxyolean-12-en-28-oic acid is used as a promising compound in pharmaceutical research and development due to its diverse biological activities, including anti-inflammatory, antioxidant, and cytotoxic properties. Its potential in treating various diseases, such as cancer and diabetes, makes it a valuable candidate for further exploration and application in the development of novel therapeutic agents.
Used in Cancer Treatment:
In the field of oncology, 2β,3β,16α,23,24-Pentahydroxyolean-12-en-28-oic acid is used as a potential anti-cancer agent. Its cytotoxic properties have been studied for their ability to target and inhibit the growth of cancer cells, making it a candidate for further research in cancer treatment strategies.
Used in Diabetes Management:
2β,3β,16α,23,24-Pentahydroxyolean-12-en-28-oic acid is also used as a potential agent in diabetes management. Its biological activities, including anti-inflammatory and antioxidant properties, suggest that it may play a role in modulating the pathophysiological processes associated with diabetes, warranting further investigation into its potential therapeutic applications in this area.
Used in Antioxidant and Anti-inflammatory Applications:
In the context of antioxidant and anti-inflammatory applications, 2β,3β,16α,23,24-Pentahydroxyolean-12-en-28-oic acid is utilized for its ability to combat oxidative stress and reduce inflammation. Its presence in various plants and its demonstrated biological activities make it a candidate for the development of natural health products and supplements aimed at promoting overall health and well-being.

InChI:InChI=1/C30H48O7/c1-25(2)10-11-30(24(36)37)18(12-25)17-6-7-20-26(3)13-19(33)23(35)29(15-31,16-32)21(26)8-9-27(20,4)28(17,5)14-22(30)34/h6,18-23,31-35H,7-16H2,1-5H3,(H,36,37)

Upstream product

• 849758-42-5 3-O-β-D-glucopyranosyl-(1->6)-β-D-glucopyranosyl-(1->6)-β-D-glucopyranosyl-2β,3β,16α,23,24-pentahydroxyolean-12-ene-28-oic acid 28-O-β-D-xylopyranosyl-(1->4)-α-L-rhamnopyranosyl-(1->2)-α-L-arabinopyranoside 

Relevant academic research and scientific papers

New triterpenoid saponins from the roots of Platycodon grandiflorum

Bioassay-directed fractionation of the antiviral active fraction of the roots of Platycodon grandiflorum leads to the isolation of three new triterpenoid saponins, platycosides G1-G3 (1-3), as well as two known saponins, platycodin D3 (4), and platycoside E (5). The structures of the new compounds were elucidated on the basis of their spectral data and chemical evidences. The isolated saponins were tested for their antiviral activities against respiratory syncytial virus (RSV), herpes simplex type 1 virus (HSV-1) and influenza type A virus (Flu A). Compound 4 showed weak anti-RSV activity.

Platycosides P and Q, two new triterpene saponins from Platycodon grandiflorum

The EtOH extract of the roots of Platycodon grandiflorum afforded two new triterpene saponins platycoside P (1) and platycoside Q (2). Their structures were elucidated based on spectroscopic means and hydrolysis products. These compounds were evaluated for inhibitory activity against LPS-induced TNF-α production in RAW 246.7 macrophages. Compounds 1 and 2 showed inhibitory activity with the inhibition ratios (%) of 38.6 and 44.1 at 50?μM, respectively.

Eight new oleanane-type triterpenoid saponins from Platycodon Root

Eight new triterpenoid saponins, platyconic acids B (1), C (2), D (3), E (4), platycodins J (5), K (6), L (7) and platycosaponin A (8), were isolated from Platycodon Root, together with twelve known compounds, and they were characterized on the basis of their spectroscopic and chemical data. The Japan Institute of Heterocyclic Chemistry.