22343-46-0Relevant academic research and scientific papers
New glycosides of the fungus Acremonium striatisporum isolated from a sea cucumber
Afiyatullov, Shamil Sh.,Kalinovsky, Anatoly I.,Kuznetsova, Tatyana A.,Pivkin, Mikhail V.,Prokofeva, Nina G.,Dmitrenok, Pavel S.,Elyakov, George B.
, p. 1047 - 1051 (2004)
Four new diterpene glycosides, virescenosides R (1), S (2), T (3), and U (4), have been isolated from a marine strain of Acremonium striatisporum KMM 4401 associated with the holothurian Eupentacta fraudatrix. Their structures have been elucidated on the basis of HRFABMS, 1D and 2D NMR (1H, 13C, DEPT, COSY-45, COSY-RCT, HSQC, HMBC, and NOESY spectra), and the results of acidic hydrolysis as 19-O-{β-D-glucopyranosyl(1→6)-β- D-altropyranosyl}-isopimara-7,15-diene-2α,3β-diol (1), 19-O-β-D-altropyranosyl-3-oxo-isopimara-8(14),15-diene-7α-ol (2), 19-O-β-o-altropyranosyl-3,7-dioxo-isopimara-8,-15-diene (3), and 19-O-β-o-altropyranosyl-3,7-dioxo-isopimara-8(14),15-diene (4). The cytotoxic activity of the virescenosides was examined.
New diterpenic altrosides of the fungus Acremonium striatisporum isolated from a sea cucumber
Afiyatullov, Shamil Sh.,Kuznetsova, Tatyana A.,Isakov, Vladimir V.,Pivkin, Mikhail V.,Prokofeva, Nina G.,Elyakov, George B.
, p. 848 - 850 (2007/10/03)
Two new diterpenic glycosides, virescenosides M (1) and N (2), have been isolated from a marine strain of Acremonium striatisporum KMM 4401 associated with the holothurian Eupentacta fraudatrix. Their structures were determined on the basis of MS and NMR data as β-D-altropyranosido-19-7-oxo-isopimara- 8,15-diene-2α,3β-diol (1) and β-D-altropyranosido-19-isopimara-7,15-diene- 2α,3β,6β-triol (2). Three other altrosides (3-5), identified as virescenosides A, B, and C from the terrestrial strain Acremonium luzulae, were also isolated. The cytotoxic activity of the virescenosides was examined.
