223508-38-1

Basic information

• Product Name: N-(1H-benzo[d]imidazol-2-yl)-3-chlorobenzimidamide
• Synonyms: N-(1H-benzo[d]imidazol-2-yl)-3-chlorobenzimidamide
• CAS NO: 223508-38-1
• Molecular Weight: 270.721
• Mol File: 223508-38-1.mol

Chemical Properties

• CAS DataBase Reference: N-(1H-benzo[d]imidazol-2-yl)-3-chlorobenzimidamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(1H-benzo[d]imidazol-2-yl)-3-chlorobenzimidamide(223508-38-1)
• EPA Substance Registry System: N-(1H-benzo[d]imidazol-2-yl)-3-chlorobenzimidamide(223508-38-1)

Safety Data

• Hazardous Substances Data: 223508-38-1(Hazardous Substances Data)

Upstream product

• 934-32-7 1H-benzimidazol-2-amine 
• 766-84-7 3-chloro-benzonitrile 

Relevant articles and documents

Syntheses of [1,2,4]triazolo[1,5-: A] benzazoles enabled by the transition-metal-free oxidative N-N bond formation

A transition-metal-free oxidative N-N bond formation strategy was developed to generate various structurally interesting [1,2,4]triazolo[1,5-a]benzazoles efficiently. The mechanism of the key oxidative N-N bond formation was investigated by using an intramolecular competition reaction. Notably, the first single crystal structure was also obtained to confirm the structure of 2-aryl[1,2,4]triazolo[1,5-a]benzimidazole.

A convenient approach to the synthesis of 2-aryl-4-alkyl-1,3,5-triazino[1,2-a]benzimidazoles

The reaction of 2-aminobenzimidazole 1 with benzonitrile in the presence of anhydrous stannic chloride gives N-(benzimidazol-2-yl)arylamidines 2 in 65-82% yield. Cyclocondensation of 2 with triethyl orthoesters affords 2-aryl-4-alkyl-1,3,5-triazino[1,2-a]