223521-08-2

Basic information

• Product Name: 5-Benzyl-4-{[1-[5-(4-chloro-phenyl)-furan-2-yl]-meth-(Z)-ylidene]-amino}-2,4-dihydro-[1,2,4]triazole-3-thione
• Synonyms: 5-Benzyl-4-{[1-[5-(4-chloro-phenyl)-furan-2-yl]-meth-(Z)-ylidene]-amino}-2,4-dihydro-[1,2,4]triazole-3-thione
• CAS NO: 223521-08-2
• Molecular Weight: 394.884
• Mol File: 223521-08-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-Benzyl-4-{[1-[5-(4-chloro-phenyl)-furan-2-yl]-meth-(Z)-ylidene]-amino}-2,4-dihydro-[1,2,4]triazole-3-thione(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Benzyl-4-{[1-[5-(4-chloro-phenyl)-furan-2-yl]-meth-(Z)-ylidene]-amino}-2,4-dihydro-[1,2,4]triazole-3-thione(223521-08-2)
• EPA Substance Registry System: 5-Benzyl-4-{[1-[5-(4-chloro-phenyl)-furan-2-yl]-meth-(Z)-ylidene]-amino}-2,4-dihydro-[1,2,4]triazole-3-thione(223521-08-2)

Safety Data

• Hazardous Substances Data: 223521-08-2(Hazardous Substances Data)

Upstream product

• 34035-03-5 5-(4-chlorophenyl)-2-furaldehyde 
• 13373-10-9 5-Benzyl-4-amino-3-mercapto-1,2,4-triazole 

Relevant articles and documents

Studies on arylfuran derivatives. Part VII. Synthesis and characterization of some Mannich bases carrying halophenylfuryl moieties as promising antibacterial agents

A series of 4-[5-(halophenyl)-2-furfurylidene)]amino-3-mercapto-5-substituted-1,2,4 -triazoles (3) were synthesized. Aminomethylation of 3 with formaldehyde and a secondary amine furnished Mannich bases, 4. Both Schiff bases and Mannich bases were characterized on the basis of IR, NMR, mass spectral data and elemental analysis. All the newly synthesized compounds were tested for their antibacterial activities. Some of them carrying morpholino and N-methylpiperazino residues were found to be promising antibacterial agents.