223541-18-2Relevant academic research and scientific papers
Cyclizations via enamine intermediates with amine dehydrogenations
M?hrle,Mehrens
, p. 214 - 224 (2007/10/03)
The mercury-edta dehydrogenation of the 4'-aminosubstituted-acetophenones 1, 8a and 9a produced the ring cleavaged derivatives 7, 11a and 12a, while the piperidine and its derivatives 10a - 10e gave rise to tetracyclic compounds 16a - 16e and to methylenedi-enamines 19a - 19d, the additionally C-1-fragment in 19a - 19d probably coming from mercury edta. With addition of m-nitrobenzaldehyde to the mercury-edta dehydrogenation of substituted phenylpiperidines another route only generated the di-enamines 22.
