Cas 223550-60-5,[4-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-butyl]-[(S)-2-((S)-3-methyl-1-phenylcarbamoyl-butylcarbamoyl)-4-phenyl-butyl]-phosphinic acid

223550-60-5

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Basic information

Product Name: [4-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-butyl]-[(S)-2-((S)-3-methyl-1-phenylcarbamoyl-butylcarbamoyl)-4-phenyl-butyl]-phosphinic acid
Synonyms:
CAS NO:223550-60-5
Molecular Formula:
Molecular Weight: 631.709
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: [4-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-butyl]-[(S)-2-((S)-3-methyl-1-phenylcarbamoyl-butylcarbamoyl)-4-phenyl-butyl]-phosphinic acid(CAS DataBase Reference)
NIST Chemistry Reference: [4-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-butyl]-[(S)-2-((S)-3-methyl-1-phenylcarbamoyl-butylcarbamoyl)-4-phenyl-butyl]-phosphinic acid(223550-60-5)
EPA Substance Registry System: [4-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-butyl]-[(S)-2-((S)-3-methyl-1-phenylcarbamoyl-butylcarbamoyl)-4-phenyl-butyl]-phosphinic acid(223550-60-5)

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Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 223550-60-5(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 223550-60-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,3,5,5 and 0 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 223550-60:
(8*2)+(7*2)+(6*3)+(5*5)+(4*5)+(3*0)+(2*6)+(1*0)=105
105 % 10 = 5
So 223550-60-5 is a valid CAS Registry Number.

223550-60-5Upstream product

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223550-60-5Relevant academic research and scientific papers

Phosphinic acid inhibitors of matrix metalloproteinases

Caldwell,Sahoo,Polo,Eversole,Lanza,Mills,Niedzwiecki,Izquierdo-Martin,Chang,Harrison,Kuo,Lin,Stein,Durette,Hagmann

, p. 323 - 328 (2007/10/03)

The matrix metalloproteinase stromelyin-1 (MMP-3) is inhibited more strongly by peptidyl phosphinic acid 7 than by its corresponding phosphonamidate and phosphonate analogs. Extending a benzyl group at P1' to a phenylethyl group in 8 further increases the potency (K(i) = 1.4 nM). Enhanced potency with an extended substituent into the P3 region was observed.

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