223676-55-9

Upstream product

• 3796-70-1 trans geranyl acetone 
• 223676-54-8 (2E,6E,10Z)-12-(2-Hydroxy-5-methoxy-phenyl)-3,7,11-trimethyl-dodeca-2,6,10-trienoic acid ethyl ester 
• 223676-53-7 (2E,6E)-10-(4-Methoxy-phenoxy)-3,7,11-trimethyl-dodeca-2,6,11-trienoic acid ethyl ester 
• 223676-52-6 (2E,6E)-10-Chloro-3,7,11-trimethyl-dodeca-2,6,11-trienoic acid ethyl ester 
• 33776-65-7 ethyl (2Z/E,6E)-3,7,11-trimethyldodeca-2,6,10-trienoate 

Downstream Products

• 223676-66-2 2,2-Dimethyl-propionic acid 2-((2Z,6E,10E)-12-hydroxy-2,6,10-trimethyl-dodeca-2,6,10-trienyl)-4-methoxy-phenyl ester 

Relevant academic research and scientific papers

Synthesis of longithorone B, a sixteen-membered farnesylated p- benzoquinone

The intramolecular coupling reactions at the C-1 position of the 10Z- farnesyl moiety appended at the 2'-position of 4'-methoxy phenol derivatives were examined with the aid of Hf(OTf)4 and LiClO4. When the phenol was protected with a TBDMS group, meta coupling predominated while para coupling occurred efficiently when protected with a pivaloyl group. The para-coupled product was transformed to longithorone B, recently isolated from a tunicate.