223690-00-4Relevant academic research and scientific papers
AZABICYCLIC SPIROETHER DERIVATIVES AS RECEPTOR ANTAGONISTS
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Page 29, (2010/02/06)
The present invention relates compounds of the formula (I): wherein Z is -CR9R10CH2- or -CH2CR9R10-; and R1, R2, R3, R4, R5 and R
A convenient method for the preparation of aryl cyclopropyl ethers from phenols
Hollingworth, Gregory J.,Dinnell, Kevin,Dickinson, Laura C.,Elliott, Jason M.,Kulagowski, Janusz J.,Swain, Christopher J.,Thomson, Christopher G.
, p. 2633 - 2636 (2007/10/03)
A general method for the synthesis of cyclopropyl ethers from phenols is described. Alkylation of a phenol using 1-iodo-1-(phenylthio)cyclopropane followed by removal of the phenylthio group furnishes the cyclopropyl ethers in modest to excellent yields. The procedure tolerates a wide range of functional groups.
