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(2S)-1-(2-nitroethenyl)-,-diphenyl-2-pyrrolidinemethanol, also known as mexiletine, is a chemical compound with potential pharmaceutical applications. It is a derivative of lidocaine and possesses properties that make it a promising candidate for the treatment of certain medical conditions.
Used in Pharmaceutical Industry:
(2S)-1-(2-nitroethenyl)-,-diphenyl-2-pyrrolidinemethanol is used as an antiarrhythmic agent for the treatment of certain types of irregular heartbeats. It functions by blocking sodium channels in the heart, which helps to stabilize the heart's electrical activity and prevent abnormal rhythms. This application is particularly relevant for the treatment of ventricular arrhythmias, which are abnormal heartbeats that originate in the lower chambers of the heart.
Additionally, (2S)-1-(2-nitroethenyl)-,-diphenyl-2-pyrrolidinemethanol, or mexiletine, is being investigated for its potential use in the treatment of neuropathic pain, indicating its versatility and potential for addressing a range of health concerns within the pharmaceutical sector.

223714-08-7

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223714-08-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 223714-08-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,3,7,1 and 4 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 223714-08:
(8*2)+(7*2)+(6*3)+(5*7)+(4*1)+(3*4)+(2*0)+(1*8)=107
107 % 10 = 7
So 223714-08-7 is a valid CAS Registry Number.

223714-08-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (2s)-1-(2-Nitroethenyl)-|á, |á-diphenyl-2-pyrrolidinemethanol

1.2 Other means of identification

Product number -
Other names ((2S)-1-(-2-Nitrovinyl)-2,3-diphenylpyrrolidin-2-yl)methanol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:223714-08-7 SDS

223714-08-7Downstream Products

223714-08-7Relevant academic research and scientific papers

Lewis acid-promoted nitroolefination of enol silyl ethers via an addition elimination process

Chen, Ji-Jun,Kawabata, Takeo,Ohnishi, Hiroshi,Shang, Muhong,Fuji, Kaoru

, p. 394 - 397 (1999)

Lewis acid-promoted nitroolefination of enol silyl ethers has been developed. Enol ethers 1, 4, 5, and 6 derived from lactones and lactams furnished nitroolefines 2, 7, 8, and 9, respectively in 60 - 99% yields by the treatment with 3 in the presence of L

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