223714-08-7 Usage
General Description
(2S)-1-(2-nitroethenyl)-,-diphenyl-2-pyrrolidinemethanol, also known as mexiletine, is a chemical compound with potential pharmaceutical applications. It is a derivative of lidocaine and is used as an antiarrhythmic agent to treat certain types of irregular heartbeats. Mexiletine works by blocking sodium channels in the heart, which helps to stabilize the heart's electrical activity and prevent abnormal rhythms. It is commonly used to treat ventricular arrhythmias, which are abnormal heartbeats that originate in the lower chambers of the heart. Mexiletine may also have potential for use in the treatment of neuropathic pain and is currently being investigated for this purpose.
Check Digit Verification of cas no
The CAS Registry Mumber 223714-08-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,3,7,1 and 4 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 223714-08:
(8*2)+(7*2)+(6*3)+(5*7)+(4*1)+(3*4)+(2*0)+(1*8)=107
107 % 10 = 7
So 223714-08-7 is a valid CAS Registry Number.
223714-08-7Relevant articles and documents
Lewis acid-promoted nitroolefination of enol silyl ethers via an addition elimination process
Chen, Ji-Jun,Kawabata, Takeo,Ohnishi, Hiroshi,Shang, Muhong,Fuji, Kaoru
, p. 394 - 397 (1999)
Lewis acid-promoted nitroolefination of enol silyl ethers has been developed. Enol ethers 1, 4, 5, and 6 derived from lactones and lactams furnished nitroolefines 2, 7, 8, and 9, respectively in 60 - 99% yields by the treatment with 3 in the presence of L
