223749-46-0 Usage
General Description
(+)-N-[2,2-Dimethyl-3(R)-hydroxy-6-(4,4,4-trifluorobutoxy)-3,4-dihydro-2H-1-benzopyran-4(S)-yl]-N-methylmethanesulfonamide, also known as Niflumic acid, is a nonsteroidal anti-inflammatory drug with potent activity against a wide range of inflammatory and painful conditions. It works by inhibiting the synthesis of prostaglandins and leukotrienes, which are mediators of inflammation and pain. This chemical is particularly effective in treating pain, inflammation, and stiffness caused by conditions such as arthritis, menstrual cramps, and injuries. It is available in several forms, including oral capsules and tablets, and it is generally well-tolerated with common side effects including nausea, indigestion, and headache. Overall, Niflumic acid is a widely used and effective medication for the management of various inflammatory and painful conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 223749-46-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,3,7,4 and 9 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 223749-46:
(8*2)+(7*2)+(6*3)+(5*7)+(4*4)+(3*9)+(2*4)+(1*6)=140
140 % 10 = 0
So 223749-46-0 is a valid CAS Registry Number.
223749-46-0Relevant articles and documents
Synthesis and activity of novel and selective Iks-channel blockers
Gerlach,Brendel,Lang,Paulus,Weidmann,Brüggemann,Busch,Suessbrich,Bleich,Greger
, p. 3831 - 3837 (2007/10/03)
Since the discovery of the IKs-potassium channel as the slowly activating component of the delayed rectifier current (Ik) in cardiac tissue, the search for blockers of this current has been intense. During the screening of KATP
