223769-26-4

Basic information

• Product Name: (S)-1-benzyloxycarbonyl-N-methyl-N-(2-naphthyl)-2-pyrrolidinecarboxamide
• CAS NO: 223769-26-4
• Molecular Weight: 388.466
• Mol File: 223769-26-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-1-benzyloxycarbonyl-N-methyl-N-(2-naphthyl)-2-pyrrolidinecarboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-benzyloxycarbonyl-N-methyl-N-(2-naphthyl)-2-pyrrolidinecarboxamide(223769-26-4)
• EPA Substance Registry System: (S)-1-benzyloxycarbonyl-N-methyl-N-(2-naphthyl)-2-pyrrolidinecarboxamide(223769-26-4)

Safety Data

• Hazardous Substances Data: 223769-26-4(Hazardous Substances Data)

Upstream product

• 86925-99-7 (S)-1-benzyloxycarbonyl-N-(2-naphthyl)-2-pyrrolidinecarboxamide 
• 74-88-4 methyl iodide 

Relevant articles and documents

Enantioselective synthesis of binaphthol derivatives by oxidative coupling of naphthol derivatives catalyzed by chiral diamine-copper complexes

A highly efficient process of aerobic oxidative coupling of 2-naphthol derivatives catalyzed by 1 mol % of Cu(OH)Cl·TMEDA has been developed. Enantioselective oxidative coupling of naphthols was achieved by the use of 10 mol % of chiral catalysts prepared from proline-derived diamines and cuprous chloride, affording the corresponding binaphthols in good enantioselectivities of up to 78% ee. The ester moiety at the 3-position of the substrate was found to be essential for the good asymmetric induction observed in the present coupling reaction.