223777-99-9

Upstream product

• 112711-16-7 (5R,5aR,8aR,9R)-9-((tert-butyldimethylsilyl)oxy)-5-(3,4,5-trimethoxyphenyl)-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one 
• 518-28-5 podofilox 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 342824-63-9 (5R,5aS,8aS,9S)-5a-Fluoro-5-(4-hydroxy-3,5-dimethoxy-phenyl)-9-(4-nitro-phenylamino)-5,8,8a,9-tetrahydro-5aH-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6-one 
• 223778-03-8 2-fluoropodophyllotoxin 

Relevant academic research and scientific papers

Antitumor agents. 207. Design, synthesis, and biological testing of 4β-anilino-2-fluoro-4′-demethylpodophyllotoxin analogues as cytotoxic and antiviral agents

2-Fluoropodophyllotoxin (11) and several 4β-anilino-2-fluoro-4′-O-demethyl analogues were synthesized and evaluated in both antineoplastic and antiviral assays. These compounds were moderately active against some cancer cell lines, but they were less acti

A high yield preparation of 2-fluoropodophyllotoxin

The high yield synthesis of 2-fluoropodophyllotoxin is presented. This preparation represents the first example of a 100% diastereospecific electrophilic fluorination.