223797-64-6 Usage
Uses
1. Used in Chemical Synthesis:
Tert-Butyl 1,5-diazocane-1-carboxylate is used as an intermediate in the synthesis of various organic compounds. Its unique structure and reactivity make it a valuable building block for creating complex molecules in the field of organic chemistry.
2. Used in Pharmaceutical Industry:
Tert-Butyl 1,5-diazocane-1-carboxylate is used as a potential candidate for drug development. Its heterocyclic properties and carbamate ester structure may offer new opportunities for the design of novel therapeutic agents with unique pharmacological profiles.
3. Used in Material Science:
Tert-Butyl 1,5-diazocane-1-carboxylate is used as a component in the development of new materials with specific properties. Its incorporation into polymers or other materials may lead to the creation of materials with improved characteristics, such as enhanced stability or novel functionalities.
4. Used in Research and Development:
Tert-Butyl 1,5-diazocane-1-carboxylate is used as a research compound for studying the properties and potential applications of azocanes and related compounds. Its synthesis and characterization can provide valuable insights into the chemistry and reactivity of this class of compounds, potentially leading to new discoveries and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 223797-64-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,3,7,9 and 7 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 223797-64:
(8*2)+(7*2)+(6*3)+(5*7)+(4*9)+(3*7)+(2*6)+(1*4)=156
156 % 10 = 6
So 223797-64-6 is a valid CAS Registry Number.
InChI:InChI=1/C11H22N2O2/c1-11(2,3)15-10(14)13-8-4-6-12-7-5-9-13/h12H,4-9H2,1-3H3
223797-64-6Relevant academic research and scientific papers
New ligands with affinity for the α4β2 subtype of nicotinic acetylcholine receptors. Synthesis, receptor binding, and 3D-QSAR modeling
Audouze, Karine,Nielsen, Elsebet ?stergaard,Olsen, Gunnar M.,Ahring, Philip,J?rgensen, Tino Dyhring,Peters, Dan,Liljefors, Tommy,Balle, Thomas
, p. 3159 - 3171 (2007/10/03)
A new series of piperazines, diazepanes, diazocanes, diazabicyclononanes, and diazabicyclodecanes with affinity for the α4β 2 subtype of nicotinic acetylcholine receptors were synthesized on the basis of results from a previous computational study. A predictive 3D-QSAR model was developed using the GRID/GOLPE approach (R2 = 0.94, Q 2 = 0.83, SDEP = 0.34). The SAR was interpreted in terms of contour maps of the PLS coefficients and in terms of a homology model of the α4β2 subtype of the nicotinic acetylcholine receptors. The results reveal that hydrogen bonding from both hydrogens on the protonated amine and from the pyridine nitrogen to a water molecule as well as van der Waals interactions between the substituent bearing the protonated amine and the receptor is of importance for ligand affinity. The combination of 3D-QSAR and homology modeling proved successful for the interpretation of structure-affinity relationships as well as the validation of the individual modeling approaches.
