2239-83-0

Usage

Uses

Used in Pharmaceutical Industry:
2-Methyl-5-pyrimidinemethanol is used as a pharmaceutical intermediate for the synthesis of various medications, particularly antiviral drugs. Its unique structure and functional groups make it a valuable component in the development of new pharmaceuticals.
Used in Organic Synthesis:
As an important building block in organic synthesis, 2-Methyl-5-pyrimidinemethanol is utilized in the creation of a wide range of chemical compounds, further expanding its applications in the pharmaceutical industry and other related fields.
Used in Antiviral Drug Development:
2-Methyl-5-pyrimidinemethanol is used as a key component in the development of antiviral drugs, where its specific chemical properties contribute to the effectiveness of these medications in combating viral infections.

InChI:InChI=1/C6H8N2O/c1-5-7-2-6(4-9)3-8-5/h2-3,9H,4H2,1H3

Upstream product

• 126504-91-4 Trimethyl<(2-methyl-5-pyrimidinyl)methyl>ammonium Hydroxide 
• 90905-33-2 2-methyl-5-pyrimidinecarbaldehyde 
• 5194-32-1 2-methylpyrimidine-5-carboxylic acid 

Downstream Products

• 126504-86-7 5-(Chloromethyl)-2-methylpyrimidine 
• 14273-46-2 (2-methylpyrimidin-5-yl)methanamine 

Relevant academic research and scientific papers

cGAS ANTAGONIST COMPOUNDS

Disclosed are novel compounds of Formula (I) that are cGAS antagonists, methods of preparation of the compounds, pharmaceutical compositions comprising the compounds, and their use in medical therapy.

NOVEL SULFONIMIDOYLPURINONE COMPOUNDS AND DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF VIRUS INFECTION

The present invention relates to compounds of formula (I), wherein R 1, R2 and R3 are as described herein, and their prodrugs or pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.

SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF

Compounds, compositions and methods are described for inhibiting the TRPC5 ion channel and disorders related to TRPC5.

SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF

Compounds, compositions and methods are described for inhibiting the TRPC5 ion channel and disorders related to TRPC5.

AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF

Compounds are provided according to formula (I), where A, B, W, X', L, R1, R3, R4b, and m' are as defined herein. Provided compounds and pharmaceutical compositions thereof are useful for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, cognitive disorders, anxiety, depression, and others.

2-Cyanophenyl fused heterocyclic compounds, and compositions and uses thereof

Fused heterocyclic compounds are provided according to formula 1: where R1, R2, R3, and m are as defined herein. Provided compounds and pharmaceutical compositions thereof are useful for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, cognitive disorders, anxiety, depression, and others.

(2,5)Pyrimidinophanes: Synthesis and Molecular Structure

The title compounds 1 and 2 are synthesized by photolytic sulfur extrusion from 2,11-dithia(2,5)pyrimidinophane 17.The molecular structures of 1 and 2 are determined by X-ray structure analysis and are discussed with regard to the steric strain in these molecules.Thermolysis of - or -trimethylammonium hydroxide (10 or 11) does not generate 1 and 2. α-Chlorination of 2,5-dimethylpyrimidine (3) with N-chlorosuccinimide provides the required precursors 4 - 6.