224313-91-1

Basic information

• Product Name: ethyl (3E)-3-(benzylimino)butanoate
• Synonyms: 5H-Thiazolo[3,2-a]pyrimidine-6-carboxamide, 7-hydroxy-5-oxo-N-2-thiazolyl-
• CAS NO: 224313-91-1
• Molecular Formula: C₁₃H₁₇NO₂
• Molecular Weight: 219.2796
• Mol File: 224313-91-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 314.3°C at 760 mmHg
• Flash Point: 126.6°C
• Density: 0.99g/cm³
• Vapor Pressure: 0.000469mmHg at 25°C
• Refractive Index: 1.5
• CAS DataBase Reference: ethyl (3E)-3-(benzylimino)butanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl (3E)-3-(benzylimino)butanoate(224313-91-1)
• EPA Substance Registry System: ethyl (3E)-3-(benzylimino)butanoate(224313-91-1)

Safety Data

• Hazardous Substances Data: 224313-91-1(Hazardous Substances Data)

Upstream product

• 96-50-4 2-thiazolylamine 
• 1186-73-8 methanetricarboxylic acid trimethyl ester 
• 224313-88-6 methyl 7-hydroxy-5-oxo-5H-<1,3>thiazolo<3,2-a>pyrimidine-6-carboxylate 

Relevant articles and documents

Methanetricarboxylates as key reagents for the simple preparation of heteroarylcarboxamides with potential biological activity. Part 2 [1]. Reaction of methanetricarboxylates with 2-aminopyridine, 2-aminopyrimidine, 2-aminothiazole and 2-aminobenzothiazole

The reaction of methanetricarboxylates 1a,b with 2-aminopyridine, 2- aminopyrimidine, 2-aminothiazole as well as 2-aminobenzothiazole yields corresponding heteroarylcarboxylic acid esters 2a,b, 5, 8, 11a,b. These heterocyclic esters were used as a starting material by the reaction with primary amines to obtaining a number of heteroarylcarboxylic amides 4a-j, 6, 10a,b, 13a-g bearing various substituents on the carboxamide group.