22454-86-0 Usage
Uses
Used in Dietary Supplements Industry:
Calcium orotate is used as a dietary supplement for supporting bone health, reducing the risk of osteoporosis, and promoting overall wellness. It is believed to improve the absorption and utilization of calcium in the body, making it a valuable addition to the diets of those seeking to maintain strong bones and muscles.
Used in Bone Health Applications:
Calcium orotate is used as a bone health supplement to support the maintenance of strong bones and reduce the risk of osteoporosis. Its enhanced calcium delivery to the cells is believed to contribute to improved bone density and strength, making it a beneficial option for individuals concerned about bone health.
Used in Muscle and Nerve Function Support:
Calcium orotate is used to support muscle function and nerve function, as calcium plays a crucial role in these processes. By improving the absorption and utilization of calcium, calcium orotate may help maintain optimal muscle and nerve health, contributing to overall well-being.
Available in various forms such as capsules, tablets, and powders, calcium orotate is generally well-tolerated with few reported side effects, making it a safe and convenient option for those looking to incorporate this mineral supplement into their daily routine.
Check Digit Verification of cas no
The CAS Registry Mumber 22454-86-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,4,5 and 4 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 22454-86:
(7*2)+(6*2)+(5*4)+(4*5)+(3*4)+(2*8)+(1*6)=100
100 % 10 = 0
So 22454-86-0 is a valid CAS Registry Number.
InChI:InChI=1/2C5H4N2O4.Ca/c2*8-3-1-2(4(9)10)6-5(11)7-3;/h2*1H,(H,9,10)(H2,6,7,8,11);/q;;+2/p-2
22454-86-0Relevant academic research and scientific papers
Orotate Complexes, II. Preparation and Crystal Structures of Calcium and Zinc Orotate(2-) Hydrates
Kumberger, Otto,Riede, Juergen,Schmidbaur, Hubert
, p. 2739 - 2742 (2007/10/02)
From aqueous solutions containing orotate (dianion of 1) and calcium or zinc ions in the molar ratio of 2:1, metal orotate(2-) hydrates are readily obtained in crystalline form at pH 9.0 and 5.4, respectively.According to an X-ray crystal structure analysis, calcium orotate tetrahydrate forms a one-dimensional coordination polymer with each orotate ligand coordinated to no less than three neighboring calcium atoms.In this cation triple, the orotate(2-) anion acts as a carboxylate-O/amide-N-chelating group for the central calcium ion, but also as a carboxylate-O/O-chelating group for the first neighboring calcium ion, and as a terminal amide-O donor for the second.Each calcium ion is thus octacoordinated and linked to three orotate(2-) anions and three water molecules.The fourth water molecule is only engaged in hydrogen bonding.The new zinc orotate(2-) phase features Zn(Or)(H2O)4 units.For the hexacoordinate zinc atom bearing four water molecules the orotate(2-) ligand also acts as an O/N-chelating group.Unlike a discrete Zn(Or)(H2O)4*H2O phase reported earlier, the lattice of the new phase contains further disordered water of crystallization, with the overall composition approaching Zn(Or)*5,5H2O.The apparent stability of the M(Or) units probably reflects the well-documented carrier function of the orotate ligand for certain divalent metal ions in biological systems.Key Words: Orotate complexes / Calcium complexes / Zinc complexes
