224629-61-2

Upstream product

• 186581-53-3 diazomethane 
• 5891-45-2 (S)-2-(benzyloxycarbonylamino)pentanedioic acid tert-butyl ester 

Downstream Products

• 204074-54-4 2-benzyloxycarbonylamino-6-[(5-benzyloxycarbonylamino-5-tert-butoxycarbonyl-2-oxo-pentyl)-(5-benzyloxycarbonylamino-5-tert-butoxycarbonyl-pentyl)-amino]-5-oxo-hexanoic acid tert-butyl ester 
• 224629-59-8 4-[(S)-2-benzyloxycarbonylamino-2-(tert-butyloxycarbonyl)ethyl]-5-[(S)-3-benzyloxycarbonylamino-3-(tert-butyloxycarbonyl)propyl]-1-[(S)-5-benzyloxycarbonylamino-5-(tert-butyloxycarbonyl)pentyl]-3-pyridiniumolate 
• 410546-13-3 6-[benzyl-(5-benzyloxycarbonylamino-5-tert-butoxycarbonyl-2-oxo-pentyl)-amino]-2-benzyloxycarbonylamino-5-oxo-hexanoic acid tert-butyl ester 
• 410546-10-0 6-[allyl-(5-benzyloxycarbonylamino-5-tert-butoxycarbonyl-2-oxo-pentyl)-amino]-2-benzyloxycarbonylamino-5-oxo-hexanoic acid tert-butyl ester 
• 410546-04-2 (S,S)-1-allyl-4-[2-benzyloxycarbonylamino-2-(tert-butoxycarbonyl)ethyl]-5-[3-benzyloxycarbonylamino-3-(tert-butoxycarbonyl)propyl]pyridinium-3-olate 
• 254106-01-9 4-[(S)-2-benzyloxycarbonylamino-2-(tert-butyloxycarbonyl)ethyl]-5-[(S)-3-benzyloxycarbonylamino-3-(tert-butyloxycarbonyl)propyl]-3-hydroxypyridine 
• 224629-58-7 (S)-2-benzyloxycarbonylamino-6-bromo-5-oxohexanoic acid tert-butyl ester 

Relevant academic research and scientific papers

Total synthesis of deoxypyridinoline, a biochemical marker of collagen turnover

A convergent synthesis of deoxypyridinoline is described which involves the assembly of a suitably polysubstituted 3-hydroxypyridinium ring starting with fully protected L-lysine and L-glutamic acid.

A practical protocol for the synthesis of 3-hydroxy-4,5-disubstituted pyridine derivatives from acyclic compounds

The paper reports a simple protocol for assembling a 3-hydroxy-4,5-disubstituted pyridine ring by reaction of allylamine or benzylamine and an α-bromo ketone and successive N-dealkylation.