224635-71-6Relevant articles and documents
Synthesis of 5-hydroxyoxaindan-2-ones and indol-5-ols from 1,4- cyclohexanedione
Ozaki, Yutaka,Quan, Zhe-Shan,Watabe, Kyouko,Kim, Sang-Won
, p. 727 - 731 (2007/10/03)
1,4-Cyclohexanedione reacted with 2-oxocarboxylic acids to give 5- hydroxyoxaindan-2-ones including homogentisic lactone in one pot. The obtained aromatic compounds were transformed into indol-5-ols in a few steps. The sequential reactions showed a significance of 1,4-cyclohexanedione as a starting material in aromatic synthesis and an alternative access to the indol-5-ols.