22473-77-4Relevant academic research and scientific papers
Syntheses, addition-eliminations, and addition-displacements of 5-(bromomethylene)hydantoins
Mathur, Naresh C.,Wong, Sau K.,Shechter, Harold
, p. 5141 - 5144 (2003)
5-(Bromomethylene)hydantoins, prepared from bromopyruvic acid and ureas in the presence of BF3, react with various nitrogen, phosphorus, sulfur, and carbon nucleophiles by addition-elimination to give the corresponding 5-(substituted-methylene)hydantoins. The 5-(bromomethylene)hydantoins also undergo acid-catalyzed reactions with nucleophiles by addition-displacement and addition-elimination processes.
