224780-72-7

Upstream product

• 224780-68-1 (3S,4R)-3-((1R)-1-<(tert-butyldimethylsilyl)oxy>ethyl)-4-<(1S,2E)-(4-benzoyloxy-1-methyl)-2-butenyl>azetidin-2-one 
• 224780-66-9 (3S,4R)-3-((1R)-1-<(tert-butyldimethylsilyl)oxy>ethyl)-4-<(1S,2E)-(4-hydroxy-1-methyl)-2-butenyl>azetidin-2-one 
• 159496-98-7 (3S,4R)-3-((1R)-1-<(tert-butyldimethylsilyl)oxy>ethyl)-4-<(1S)-1-(formyl)ethyl>azetidin-2-one 
• 111187-44-1 3-<1-<1-<(tert-butyldimethylsilyl)oxy>ethyl>>-4-<2-(1-hydroxy-2-methylethyl)>azetidin-2-one 
• 105320-15-8 (3S,4S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-4-(1-hydroxymethyl-vinyl)-azetidin-2-one 
• 541-41-3 chloroformic acid ethyl ester 
• 224780-70-5 (3S,4R)-3-((1R)-1-<(tert-butyldimethylsilyl)oxy>ethyl)-4-<(1S,2E)-(4-benzoyloxy-1-methyl)-2-butenyl>-1-<(ethoxycarbonyl)methyl>azetidin-2-one 

Relevant academic research and scientific papers

Synthesis of 1β-methylcarbapenem antibiotic precursors by cyclization using π-allylpalladium complexes

An efficient diastereoselective multi-step synthesis of bicyclic 1β- methylcarbapenem antibiotic precursors has been developed, starting from the commercially available 4-acetoxyazetidin-2-one 4. Chiral ruthenium catalysts are used in the hydrogenation st