224780-82-9Relevant academic research and scientific papers
Synthesis of 1β-methylcarbapenem antibiotic precursors by cyclization using π-allylpalladium complexes
Galland, Jean-Christophe,Roland, Sylvain,Malpart, Joel,Savignac, Monique,Genet, Jean-Pierre
, p. 621 - 626 (1999)
An efficient diastereoselective multi-step synthesis of bicyclic 1β- methylcarbapenem antibiotic precursors has been developed, starting from the commercially available 4-acetoxyazetidin-2-one 4. Chiral ruthenium catalysts are used in the hydrogenation st
