224789-21-3

Basic information

• Product Name: 2-(2-ETHOXYPHENYL)-5-METHYL-7-PROPYL-3H-IMIDAZOL[5,1-F][1,2,4]-TRIAZIN-4-ONE
• Synonyms: 2-(2-ETHOXYPHENYL)-5-METHYL-7-PROPYL-3H-IMIDAZOL[5,1-F][1,2,4]-TRIAZIN-4-ONE;Imidazo[5,1-f][1,2,4]triazin-4(3H)-one,2-[2-ethoxylphenyl]-5-methyl-7;2-(2-Ethoxyphenyl)-5-methyl-7-propyl-imidazo[5,1-f][1,2,4]triazin-4(1H)-one;2-(2-ethoxyphenyl)-5-Methyl-7-propyliMidazo [5,1-f][1,2,4]triazin-4(3H)-one;IMidazo[5,1-f][1,2,4]triazin-4(1H)-one,2-(2-ethoxyphenyl)-5-Methyl-7-propyl-;Vardenafil Intermediate
• CAS NO: 224789-21-3
• Molecular Formula: C₁₇H₂₀N₄O₂
• Molecular Weight: 312.37
• EINECS: 1308068-626-2
• Product Categories: Heterocyclic Compounds;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 224789-21-3.mol
• Article Data: 9

Chemical Properties

• Melting Point: 198-200°C
• Boiling Point: 519.699 °C at 760 mmHg
• Flash Point: 268.105 °C
• Appearance: Pale yellow solid
• Density: 1.266 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.632
• Storage Temp.: -20°C Freezer
• PKA: 10.08±0.20(Predicted)
• Water Solubility: 6.9mg/L at 20℃
• CAS DataBase Reference: 2-(2-ETHOXYPHENYL)-5-METHYL-7-PROPYL-3H-IMIDAZOL[5,1-F][1,2,4]-TRIAZIN-4-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-ETHOXYPHENYL)-5-METHYL-7-PROPYL-3H-IMIDAZOL[5,1-F][1,2,4]-TRIAZIN-4-ONE(224789-21-3)
• EPA Substance Registry System: 2-(2-ETHOXYPHENYL)-5-METHYL-7-PROPYL-3H-IMIDAZOL[5,1-F][1,2,4]-TRIAZIN-4-ONE(224789-21-3)

Safety Data

• Hazardous Substances Data: 224789-21-3(Hazardous Substances Data)

Usage

Chemical Properties

Pale Yellow Solid

Uses

Different sources of media describe the Uses of 224789-21-3 differently. You can refer to the following data:
1. Vardenafil intermediate
2. 2-(2-Ethoxyphenyl)-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one is a Vardenafil (V098001) intermediate.

Flammability and Explosibility

Nonflammable

InChI:InChI=1/C17H20N4O2/c1-4-8-14-18-11(3)15-17(22)19-16(20-21(14)15)12-9-6-7-10-13(12)23-5-2/h6-7,9-10H,4-5,8H2,1-3H3,(H,19,20,22)

Synthetic route

N-{1-[3-(2-ethoxyphenyl)-5-oxo-4,5-dihydro-[1,2,4]triazin-6-yl]ethyl}butyroamide (927690-90-2) → 2-(2-ethoxy-phenyl)-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one (224789-21-3)

Conditions	Yield
With trichlorophosphate In toluene for 2h; Reflux;	78%
With trichlorophosphate
With trichlorophosphate In 1,2-dichloro-ethane for 2h; Reflux;
With trichlorophosphate In 1,2-dichloro-ethane for 2h; Reflux;

3-(2-ethoxy-benzoylamino)-5-methyl-2-propyl-3H-imidazole-4-carboxamide (865444-90-2) → 2-(2-ethoxy-phenyl)-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one (224789-21-3)

Conditions	Yield
With potassium tert-butylate In tert-butyl alcohol at 160℃; for 30h;	72%
With potassium tert-butylate In tert-butyl alcohol at 160℃; for 30h; Sealed tube;	72%

5-methyl-2-propyl-3H-imidazole-4-carboxamide (865444-88-8) → 2-(2-ethoxy-phenyl)-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one (224789-21-3)

Conditions	Yield
Multi-step reaction with 3 steps 1.1: lithium hexamethyldisilazane / dimethylformamide; tetrahydrofuran / 0.17 h / -10 °C 1.2: 41 percent / Ph2P(O)ONH2 / tetrahydrofuran; dimethylformamide / 20 °C 2.1: 52 percent / pyridine / 2 h / 60 °C 3.1: 72 percent / KOtBu / 2-methyl-propan-2-ol / 30 h / 160 °C View Scheme

3-amino-5-methyl-2-propyl-3H-imidazole-4-carboxamide (865444-89-9) → 2-(2-ethoxy-phenyl)-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one (224789-21-3)

Conditions	Yield
Multi-step reaction with 2 steps 1: 52 percent / pyridine / 2 h / 60 °C 2: 72 percent / KOtBu / 2-methyl-propan-2-ol / 30 h / 160 °C View Scheme

ethyl 5-methyl-2-propyl-3H-imidazole-4-carboxylate (146650-89-7) → 2-(2-ethoxy-phenyl)-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one (224789-21-3)

Conditions	Yield
Multi-step reaction with 4 steps 1.1: 53 percent / ammonium hydroxide / 24 h / 130 °C 2.1: lithium hexamethyldisilazane / dimethylformamide; tetrahydrofuran / 0.17 h / -10 °C 2.2: 41 percent / Ph2P(O)ONH2 / tetrahydrofuran; dimethylformamide / 20 °C 3.1: 52 percent / pyridine / 2 h / 60 °C 4.1: 72 percent / KOtBu / 2-methyl-propan-2-ol / 30 h / 160 °C View Scheme

2-butyrylaminopropionic acid (59875-04-6) → 2-(2-ethoxy-phenyl)-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one (224789-21-3)

Conditions	Yield
Multi-step reaction with 3 steps 1: Py; DMAP 2: POCl3 View Scheme
Multi-step reaction with 3 steps 1.1: dmap; pyridine / tetrahydrofuran / 4 h / Reflux 2.1: hydrazine hydrate / ethanol / 20 °C 2.2: 3.25 h / Reflux 3.1: trichlorophosphate / 1,2-dichloro-ethane / 2 h / Reflux View Scheme
Multi-step reaction with 3 steps 1: dmap; pyridine / tetrahydrofuran / 4 h / Reflux 2: ethanol / 3 h / Reflux 3: trichlorophosphate / 1,2-dichloro-ethane / 2 h / Reflux View Scheme

2-ethoxybenzonitrile (6609-57-0) → 2-(2-ethoxy-phenyl)-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one (224789-21-3)

Conditions	Yield
Multi-step reaction with 4 steps 1: AlMeClNH2 2: N2H4 3: POCl3 View Scheme
Multi-step reaction with 3 steps 1.1: trimethylaluminum; ammonium chloride / toluene / 7 h / 0 - 80 °C 2.1: hydrazine hydrate / ethanol / 20 °C 2.2: 3.25 h / Reflux 3.1: trichlorophosphate / 1,2-dichloro-ethane / 2 h / Reflux View Scheme
Multi-step reaction with 4 steps 1.1: amino(methyl)aluminum chloride / toluene / 6 h / 80 °C 2.1: hydrazine hydrate / ethanol / 20 °C 2.2: Reflux 3.1: ethanol / 3 h / Reflux 4.1: trichlorophosphate / 1,2-dichloro-ethane / 2 h / Reflux View Scheme

2-ethoxy-benzamidine hydrochloride (18637-00-8) → 2-(2-ethoxy-phenyl)-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one (224789-21-3)

Conditions	Yield
Multi-step reaction with 3 steps 1: N2H4 2: POCl3 View Scheme

ethyl 3-butyramido-2-oxobutyrate (68282-26-8) → 2-(2-ethoxy-phenyl)-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one (224789-21-3)

Conditions	Yield
Multi-step reaction with 2 steps 1: POCl3 View Scheme
Multi-step reaction with 2 steps 1.1: hydrazine hydrate / ethanol / 20 °C 1.2: 3.25 h / Reflux 2.1: trichlorophosphate / 1,2-dichloro-ethane / 2 h / Reflux View Scheme
Multi-step reaction with 2 steps 1: ethanol / 3 h / Reflux 2: trichlorophosphate / 1,2-dichloro-ethane / 2 h / Reflux View Scheme

2-ethoxybenzimidohydrazide (889943-46-8) → 2-(2-ethoxy-phenyl)-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one (224789-21-3)

Conditions	Yield
Multi-step reaction with 2 steps 1: POCl3 View Scheme
Multi-step reaction with 2 steps 1: ethanol / 3 h / Reflux 2: trichlorophosphate / 1,2-dichloro-ethane / 2 h / Reflux View Scheme

C9H13N3O*ClH + ethyl 3-butyramido-2-oxobutyrate (68282-26-8) → 2-(2-ethoxy-phenyl)-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one (224789-21-3)

Conditions	Yield
Stage #1: C9H13N3O*ClH; ethyl 3-butyramido-2-oxobutyrate In ethanol at 70℃; for 4h; Stage #2: With trichlorophosphate In 1,2-dichloro-ethane for 2h; Heating / reflux;

2-butyrylaminopropionic acid (59875-04-6) + 2-ethoxy-benzamidine hydrochloride (18637-00-8) + Ethyl oxalyl chloride (4755-77-5) → 2-(2-ethoxy-phenyl)-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one (224789-21-3)

Conditions	Yield
With pyridine; sodium hydrogencarbonate; hydrazine hydrate; trichlorophosphate In tetrahydrofuran; ethanol; ethyl acetate; 1,2-dichloro-ethane	4.00 g (28%)

3-(2-ethoxyphenyl)-6-ethyl-4H-[1,2,4]triazin-5-one (1417529-52-2) → 2-(2-ethoxy-phenyl)-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one (224789-21-3)

Conditions	Yield
Multi-step reaction with 4 steps 1.1: N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) / tetrachloromethane / 14 h / Reflux; Inert atmosphere 2.1: ammonia / tetrahydrofuran / 20 °C 3.1: tertiary amine / dichloromethane / 0.08 h / Cooling 3.2: 1.17 h / 0 - 20 °C 4.1: trichlorophosphate / toluene / 2 h / Reflux View Scheme

6-(1-bromoethyl)-3-(2-ethoxyphenyl)-4H-[1,2,4]triazin-5-one (1417529-54-4) → 2-(2-ethoxy-phenyl)-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one (224789-21-3)

Conditions	Yield
Multi-step reaction with 3 steps 1.1: ammonia / tetrahydrofuran / 20 °C 2.1: tertiary amine / dichloromethane / 0.08 h / Cooling 2.2: 1.17 h / 0 - 20 °C 3.1: trichlorophosphate / toluene / 2 h / Reflux View Scheme

C13H16N4O2 (1417529-56-6) → 2-(2-ethoxy-phenyl)-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one (224789-21-3)

Conditions	Yield
Multi-step reaction with 2 steps 1.1: tertiary amine / dichloromethane / 0.08 h / Cooling 1.2: 1.17 h / 0 - 20 °C 2.1: trichlorophosphate / toluene / 2 h / Reflux View Scheme

2-Ethoxybenzamidine (53623-81-7) → 2-(2-ethoxy-phenyl)-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one (224789-21-3)

Conditions	Yield
Multi-step reaction with 2 steps 1.1: hydrazine hydrate / ethanol / 20 °C 1.2: 3.25 h / Reflux 2.1: trichlorophosphate / 1,2-dichloro-ethane / 2 h / Reflux View Scheme
Multi-step reaction with 3 steps 1.1: hydrazine hydrate / ethanol / 20 °C 1.2: Reflux 2.1: ethanol / 3 h / Reflux 3.1: trichlorophosphate / 1,2-dichloro-ethane / 2 h / Reflux View Scheme

2-(2-ethoxy-phenyl)-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one (224789-21-3) → 4-ethoxy-3-(5-methyl-4-oxo-7-propyl-3,4-dihydroimidazo[5,1-f][1,2,4]triazin-2-yl)-benzenelsulfonic acid chloride (224789-26-8)

Conditions	Yield
With chlorosulfonic acid at 0 - 20℃;	91%
With chlorosulfonic acid for 12h; Cooling with ice;	76%
With chlorosulphuric acid for 12h; Cooling with ice;	76%

2-(2-ethoxy-phenyl)-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one (224789-21-3) → 2-(2-ethoxy-5-iodo-phenyl)-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4(3H)-one

Conditions	Yield
With N-iodo-succinimide; trifluoroacetic acid at 0 - 20℃;	79%
With N-iodo-succinimide; trifluoroacetic acid at 0 - 20℃;	79%
With N-iodo-succinimide In trifluoroacetic acid at 0 - 20℃;	71%
With N-iodo-succinimide; trifluoroacetic acid at 0 - 20℃;

2-(2-ethoxy-phenyl)-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one (224789-21-3) → 2-(2-ethoxy)-phenyl-5-methyl-7-n-propyl-3H-imidazolo[5,1-f][1,2,4]triazine-4-thione

Conditions	Yield
Stage #1: 2-(2-ethoxy-phenyl)-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one With pyridine; diphosphorus pentasulfide In toluene for 6h; Reflux; Stage #2: With ammonia; water In ethanol for 0.5h; Reflux;	72%
With pyridine; tetraphosphorus decasulfide for 6h; Reflux;	72%

4-ethylpiperazine (5308-25-8) + 2-(2-ethoxy-phenyl)-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one (224789-21-3) → vardenafil (224785-90-4)

Conditions	Yield
Stage #1: 2-(2-ethoxy-phenyl)-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one With chlorosulfonic acid at 0 - 22℃; for 0.75h; Stage #2: 4-ethylpiperazine In dichloromethane at -3 - 25℃; for 0.75h; Product distribution / selectivity;

4-ethylpiperazine (5308-25-8) + citric acid (77-92-9) + 2-(2-ethoxy-phenyl)-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one (224789-21-3) → vardenafil citrate (1193386-64-9)

Conditions	Yield
Stage #1: 2-(2-ethoxy-phenyl)-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one With chlorosulfonic acid at -5 - 20℃; Stage #2: 4-ethylpiperazine With sodium hydroxide In tetrahydrofuran; water at 15℃; pH=9 - 9.5; Stage #3: citric acid In tetrahydrofuran at 50 - 70℃;

2-(2-ethoxy-phenyl)-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one (224789-21-3) → vardenafil (224785-90-4)

Conditions	Yield
Multi-step reaction with 2 steps 1.1: chlorosulfonic acid / -5 - 20 °C 1.2: 15 °C / pH 9 - 9.5 1.3: 50 - 70 °C 2.1: sodium hydroxide / water / pH 9 - 10 View Scheme
Multi-step reaction with 2 steps 1: chlorosulfonic acid / 0 - 5 °C 2: dichloromethane / 25 - 30 °C View Scheme

2-(2-ethoxy-phenyl)-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one (224789-21-3) → 2-[2-ethoxy-5-(4-ethyl-piperazine-1-sulphonyl)-phenyl]-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one hydrochloride

Conditions	Yield
Multi-step reaction with 3 steps 1.1: chlorosulfonic acid / -5 - 20 °C 1.2: 15 °C / pH 9 - 9.5 1.3: 50 - 70 °C 2.1: sodium hydroxide / water / pH 9 - 10 3.1: hydrogenchloride / water; acetone View Scheme
Multi-step reaction with 3 steps 1: chlorosulfonic acid / 0 - 5 °C 2: dichloromethane / 25 - 30 °C 3: hydrogenchloride; water / acetone View Scheme

2-(2-ethoxy-phenyl)-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one (224789-21-3) → 2,2'-[(piperazine-1,4-disulfonyl)bis(2-ethoxy-5,1-phenylene)]-bis[5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(3H)-one] (1255919-03-9)

Conditions	Yield
Multi-step reaction with 2 steps 1: chlorosulfonic acid / 0 - 5 °C 2: triethylamine / dichloromethane / 0.5 h / 25 - 30 °C View Scheme

2-(2-ethoxy-phenyl)-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one (224789-21-3) → N-{[4-ethoxy-3-(5-methyl-4-oxo-7-propyl-3,4-dihydroimidazo[5,1-f]-1,2,4-triazin-2-yl) phenyl]sulfonyl}glycene (448184-54-1)

Conditions	Yield
Multi-step reaction with 2 steps 1.1: chlorosulfonic acid / 0 - 5 °C 2.1: sodium hydroxide / water / 0.5 h / 25 - 30 °C 2.2: 2.5 h / 2 - 20 °C View Scheme

2-(2-ethoxy-phenyl)-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one (224789-21-3) → C19H26N6O4S (448184-52-9)

Conditions	Yield
Multi-step reaction with 2 steps 1: chlorosulfonic acid / 0 - 5 °C 2: dichloromethane / 1.33 h / 2 °C View Scheme

2-(2-ethoxy-phenyl)-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one (224789-21-3) → {[2-({[4-ethoxy-3-(5-methyl-4-oxo-7-propyl-3,4-dihydroimidazo[5,1-f]-1,2,4-triazin-2-yl)phenyl]sulfonyl}amino)ethyl]amino}(oxo)acetic acid (448184-56-3)

Conditions	Yield
Multi-step reaction with 4 steps 1: chlorosulfonic acid / 0 - 5 °C 2: dichloromethane / 1.33 h / 2 °C 3: triethylamine / 0.25 h / 25 - 30 °C 4: water; sodium hydroxide / methanol / 0.25 h / 25 °C View Scheme

2-(2-ethoxy-phenyl)-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one (224789-21-3) → C23H30N6O7S

Conditions	Yield
Multi-step reaction with 3 steps 1: chlorosulfonic acid / 0 - 5 °C 2: dichloromethane / 1.33 h / 2 °C 3: triethylamine / 0.25 h / 25 - 30 °C View Scheme

2-(2-ethoxy-phenyl)-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one (224789-21-3) → 2-{2-ethoxy-5-[(4-ethyl-4-hydroxy-4λ5-piperazin-1-yl)sulfonyl]phenyl}-5-methyl-7-propyl imidazo-[5,1-f]-1,2,4-triazin-4(3H)-one N-oxide (448184-48-3)

Conditions	Yield
Multi-step reaction with 3 steps 1: chlorosulfonic acid / 0 - 5 °C 2: dichloromethane / 25 - 30 °C 3: peracetic acid / dichloromethane / 2 h / 0 - 5 °C View Scheme

2-(2-ethoxy-phenyl)-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one (224789-21-3) → 2-{2-ethoxy-5-[(3-oxo-1-piperazinyl)sulfonyl]phenyl}-5-methyl-7-propylimidazo[5,1-f]-1,2,4-triazin-4(3H)-one (448184-58-5)

Conditions	Yield
Multi-step reaction with 2 steps 1: chlorosulfonic acid / 0 - 5 °C 2: dichloromethane / 0.5 h / 25 - 30 °C View Scheme

2-(2-ethoxy-phenyl)-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one (224789-21-3) → vardenafil hydrochloride

Conditions	Yield
Multi-step reaction with 3 steps 1: chlorosulfonic acid / dichloromethane / 24 h / 23 - 90 °C 2: dichloromethane 3: hydrogenchloride / water; acetone / 50 °C View Scheme

Upstream product

• 889943-46-8 2-ethoxybenzimidohydrazide 
• 18637-00-8 2-ethoxy-benzamidine hydrochloride 
• 6609-57-0 2-ethoxybenzonitrile 
• 59875-04-6 2-butyrylaminopropionic acid 
• 53623-81-7 2-Ethoxybenzamidine 
• 1417529-56-6 C₁₃H₁₆N₄O₂ 
• 1417529-54-4 6-(1-bromoethyl)-3-(2-ethoxyphenyl)-4H-[1,2,4]triazin-5-one 
• 1417529-52-2 3-(2-ethoxyphenyl)-6-ethyl-4H-[1,2,4]triazin-5-one 
• 4755-77-5 Ethyl oxalyl chloride 
• 68282-26-8 ethyl 3-butyramido-2-oxobutyrate 
• 146650-89-7 ethyl 5-methyl-2-propyl-3H-imidazole-4-carboxylate 
• 865444-89-9 3-amino-5-methyl-2-propyl-3H-imidazole-4-carboxamide 
• 865444-88-8 5-methyl-2-propyl-3H-imidazole-4-carboxamide 
• 865444-90-2 3-(2-ethoxy-benzoylamino)-5-methyl-2-propyl-3H-imidazole-4-carboxamide 

Downstream Products

• 224789-26-8 4-ethoxy-3-(5-methyl-4-oxo-7-propyl-3,4-dihydroimidazo[5,1-f][1,2,4]triazin-2-yl)benzenesulfonic acid chloride 
• 224785-90-4 vardenafil 
• 1134191-30-2 C₂₅H₃₄N₆O₆S 
• 1134191-27-7 2-(4-(4-ethoxy-3-(5-methyl-4-oxo-7-propyl-1,4-dihydroimidazo[1,5-f][1,2,4]triazin-2-yl)phenylsulfonyl)piperazin-1-yl)acetic acid 
• 1134191-22-2 4-(5-thioxo-5H-1,2-dithiol-3-yl)phenyl 2-(4-(4-ethoxy-3-(5-methyl-4-oxo-7-propyl-1,4-dihydroimidazo[1,5-f][1,2,4]triazin-2-yl)phenylsulfonyl)piperazin-1-yl)acetate 
• 437717-43-6 4-ethoxy-3-(5-methyl-4-oxo-7-propyl-3,4-dihydroimidazo[5,1-f][1,2,4]triazine-2-yl)phenylsulfonic acid 

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