224947-57-3

Upstream product

• 762-72-1 allyl-trimethyl-silane 
• 1779-49-3 Methyltriphenylphosphonium bromide 
• 194423-23-9 [(2R,6R)-6-(3-Benzyloxy-propyl)-5,6-dihydro-2H-pyran-2-yl]-acetaldehyde 

Relevant academic research and scientific papers

InBr3-catalyzed stereoselective synthesis of trans-2,6-disubstituted 3,6-dihydro-2H-pyrans

A new method for the stereoselective synthesis of trans-2,6-disubstituted 3,6-dihydro-2H-pyrans with a variety of substitution patterns is described, involving Lewis acid induced tandem allylation or cyanation of δ-hydroxy-α,β-unsaturated aldehydes to pro

Synthesis of trans-syn-trans fused bis-pyrans via endo-selective cyclizations of cyclic sulfates

Acid-catalyzed cyclization of hydroxy-cyclic sulfates occurs with endo- regioselectivity affording bispyran products from substrates in which the nucleophilic hydroxyl and electrophilic cyclic sulfate groups are 1,2-trans- substituted on a cyclic pyran template. This methodology is demonstrated in an enantioselective synthesis of the trans-syn-trans fused AB cyclic ether rings of the brevetoxin natural products.