22498-68-6Relevant academic research and scientific papers
Reductive amination of ethyl levulinate to pyrrolidones over AuPd nanoparticles at ambient hydrogen pressure
Muzzio, Michelle,Yu, Chao,Lin, Honghong,Yom, Typher,Boga, Dilek A.,Xi, Zheng,Li, Na,Yin, Zhouyang,Li, Junrui,Dunn, Joshua A.,Sun, Shouheng
supporting information, p. 1895 - 1899 (2019/04/29)
Herein, we describe a AuPd catalyst for selective and solventless conversion of ethyl levulinate (EL) and amines to pyrrolidones under ambient pressure. The optimized Au66Pd34 nanoparticle catalyst was stable and reusable over 10 runs. AuPd catalysis was extended to reductive amination of levulinic acid and 4-acetylbutyric acid, providing a green chemistry approach under milder conditions not only to pyrrolidones, but also to piperidines, both of which are important scaffolds in designing polymers, natural products and pharmaceuticals.
Synthesis of (+)-coniceine via reductive photocyclization of dienamides: an entry to indolizidines
Hjelmgaard, Thomas,Gardette, Daniel,Tanner, David,Aitken, David J.
, p. 671 - 678 (2007/10/03)
This paper describes the establishment of a new synthetic route to the hydrobromide salt of (+)-coniceine 1 with high enantiopurity in five steps and 8% overall yield. The key step is the reductive photocyclization of an acyclic chiral dienamide, for whic
