225-54-7Relevant academic research and scientific papers
Ligand-free palladium-catalyzed facile construction of tetra cyclic dibenzo[b,h][1,6]naphthyridine derivatives: Domino sequence of intramolecular C-H bond arylation and oxidation reactions
Singh, Jay Bahadur,Chandra Bharadwaj, Kishor,Gupta, Tanu,Singh, Radhey M.
, p. 26993 - 26999 (2016/03/25)
A ligand-free Pd-catalyzed approach has been developed for the synthesis of dibenzo-fused naphthyridines. The reaction involves a one-pot domino sequence of reactions involving C-H functionalisation and oxidation. The reaction was applicable to a wide range of substrates, giving the required product. Further fluorescence studies were performed where the Stoke's shift was found to be dependent on the polarity of the solvent.
Synthesis, characterization and antimicrobial activities of fused 1,6-naphthyridines
Suresh,Dhanabal,Nandha Kumar,Mohan
, p. 2375 - 2379 (2007/10/03)
An easy two-steps synthesis of 1,6-naphthyridines (4a-c, 7a-c, 10a-c, 14a-c) has been arrived from 3-formylquinolin-2(1H)-ones 1a-c and respective arylamines (2, 5, 8, 12) which underwent condensation and aromatized by dehydration with the help of PPA. All the synthesized compounds have been biologically screened for their antibacterial and antifungal activities.
