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4-Trifluoromethoxyphenyl trifluoromethyl sulfone is a chemical compound characterized by its molecular formula C8H4F6O3S. It features a phenyl ring with a trifluoromethoxy group at the 4-position and a trifluoromethyl sulfone group attached to the same carbon. The trifluoromethoxy group consists of an oxygen atom bonded to a carbon atom, which in turn is bonded to three fluorine atoms, while the trifluoromethyl sulfone group has a sulfur atom bonded to a carbon atom, which is further bonded to three fluorine atoms and an oxygen atom. 4-trifluoromethoxyphenyl trifluoromethyl sulfone is known for its stability and reactivity, which can be utilized in various chemical reactions and synthesis processes. It is often used in the production of pharmaceuticals and agrochemicals due to its unique properties and ability to form stable intermediates.

2250-33-1

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2250-33-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2250-33-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,2,5 and 0 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 2250-33:
(6*2)+(5*2)+(4*5)+(3*0)+(2*3)+(1*3)=51
51 % 10 = 1
So 2250-33-1 is a valid CAS Registry Number.

2250-33-1Downstream Products

2250-33-1Relevant academic research and scientific papers

Rational Design and Development of Low-Price, Scalable, Shelf-Stable and Broadly Applicable Electrophilic Sulfonium Ylide-Based Trifluoromethylating Reagents

Ge, Hangming,Ling, Yijing,Liu, Yafei,Lu, Long,Shen, Qilong

, p. 1667 - 1682 (2021)

The development of two highly reactive electrophilic trifluoromethylating reagents (trifluoromethyl)(4-nitrophenyl)bis(carbomethoxy)methylide (1g) and (trifluoromethyl)(3-chlorophenyl)bis(carbomethoxy)methylide (1j) through structure-activity study was described. Under mild conditions, reagent 1g reacted with β-ketoesters and silyl enol ethers to give α-trifluoromethylated-β-ketoesters or α-trifluoromethylated ketones in high yields. In addition, reagent 1g could serve as a trifluoromethyl radical for a variety of trifluoromethylative transformations under visible light irradiation, including radical trifluoromethylation of electron-rich indoles and pyrroles and sodium aryl sulfinates as well as trifluoromethylative difunctionalization with styrene derivatives. On the other hand, as a complimentary, under reductive coupling conditions, reagent 1j reacted with a variety of (hetero)aryl iodides for the formation of trifluoromethylated (hetero)arenes.

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