2250-56-8Relevant academic research and scientific papers
Friedel–Crafts Type Methylation with Dimethylhalonium Salts
H?mmerling, Sebastian,Vo?nacker, Patrick,Steinhauer, Simon,Beckers, Helmut,Riedel, Sebastian
, p. 14377 - 14384 (2020/10/12)
The dimethylchloronium salt [Me2Cl][Al(OTeF5)4] is used to methylate electron-deficient aromatic systems in Friedel–Crafts type reactions as shown by the synthesis of N-methylated cations, such as [MeNC5F5]+, [MeNC5F4I]+, and [MeN3C3F3]+. To gain a better understanding of such fundamental Friedel–Crafts reactions, the role of the dimethylchloronium cation has been evaluated by quantum-chemical calculations.
