225095-43-2Relevant academic research and scientific papers
One-pot synthesis of pyrido[2,3-d]pyrimidine-2-thiones and a study of their reactivity towards some reagents
El-Gazzar,Hafez,Yakout
, p. 1303 - 1312 (2007)
A series of pyrido[2,3-d]pyrimidine-2-thione derivatives (5a-c) were synthesized by the one-pot reaction of the appropriate aldehyde, malononitrile and 6-aminothiouracil (1) in dimethyl-formamide. The same compounds were also synthesized by the reaction o
Electrocatalytic multicomponent assembling of aminouracils, aldehydes and malononitrile: An efficient approach to 7-aminopyrido[2,3-d]pyrimidine-6-carbonitrile derivatives
Kazemi-Rad, Reyhaneh,Azizian, Javad,Kefayati, Hassan
, p. 29 - 34 (2016/02/18)
The electrocatalytic multicomponent transformation of 6-aminouracils, aromatic aldehydes and malononitrile in ethanol in an undivided cell in the presence of potassium bromide as an electrolyte leads to 7-aminopyrido[2,3- -d]pyrimidine-6-carbonitrile deri
Enviro-economic, ultrasound-assisted one-pot, three-component synthesis of pyrido[2,3-d]pyrimidines in aqueous medium
Hussein, Essam M.
experimental part, p. 231 - 237 (2012/06/30)
Tetra-n-butyl ammonium bromide (TBAB) was found to be an efficient phase-transfer catalyst for the synthesis of pyrido[2,3-d]pyrimidines by one-pot reaction of 6-aminouracils, aromatic aldehydes, and malononitrile or ethyl cyanoacetate in water under ultr
One-pot synthesis of some new pyrido[2,3-d]pyrimidine derivatives catalyzed by sodium lauryl sulfate in aqueous media
Li, Sheng-Hui,Shen, Yan-Hong,Gao, Na,Li, Ji-Tai
experimental part, p. 779 - 784 (2011/12/01)
A series of pyrido[2,3-d]pyrimidine derivatives were synthesized by the three-component reaction of aromatic aldehyde, malononitrile and 6-amino-4-hydroxy-2-mercaptopyrimidine catalyzed by sodium lauryl sulfate (SDS) in aqueous media. It was interesting t
A facile one-pot synthesis of pyrido[2,3-d]pyrimidines and pyrido[2,3- d:6,5-d']dipyrimidines
Youssif, Shaker,El-Bahaie, Said,Nabih, Esam
, p. 112 - 113 (2007/10/03)
The reactions of enaminones (6-aminouracils) 1a-c and 4 with cyano olefins 2a-b and 5a-f led to the formation of pyrido[2,3-d]pyrimidines. 3a-f and 6a-f in good yield, while the treatment of 4-amino-2-thiouracil 4 with aromatic aldehydes afforded pyridodipyrimidines 7a-c.
