22515-82-8Relevant articles and documents
Synthesis and cytotoxic properties of some cyclic acetals of diols and their dichlorocyclopropyl derivatives
Raskil’dina,Kuzmina, U. Sh.,Dzhumaev, Sh. Sh.,Borisova, Yu. G.,Ishmetova,Vakhitova, Yu. V.,Zlotskii
, p. 475 - 478 (2021)
Cyclic acetals of ethylene glycol, cis-but-2-ene-1,4-diol and their dichlorocyclopropyl derivatives were synthesized. Compounds simultaneously containing the gem-dichlorocyclopropane and 1,3-dioxacycloalkane cycles are shown to exhibit cytotoxic activity against the HEK293, SH-SY5Y, HepG2, MCF-7, A549, and Jurkat cell lines. The obtained results open up prospects for further studies of antitumor activity of 2-(2,2-dichlorocyclopropyl)-2-ethyl-1,3-dioxolane.
A Convenient Preparation of Ethyl Vinyl Ketone
Byrne, Brian,Wengenroth, Karl J.
, p. 870 - 871 (2007/10/02)
A four-step synthesis of ethyl vinyl ketone conveniently gives 67percent overall yield.