22517-46-0Relevant academic research and scientific papers
Transition-metal free N-arylation of cyanamides by diaryliodonium triflates in aqueous media
Li, Jihui,Zheng, Xinyi,Li, Wei,Zhou, Wei,Zhu, Wen,Zhang, Yucang
supporting information, p. 77 - 80 (2016/01/12)
An operationally simple protocol is established for the synthesis of disubstituted cyanamides through the transition-metal free N-arylation of cyanamides by diaryliodonium triflates in aqueous media. Both alkyl and aryl cyanamides are well compatible with the mild reaction conditions. The one-pot synthesis of ureas is also possible through sequential arylation and hydrolysis of cyanamides, diaryliodonium triflates and H2O with good yields.
An efficient synthesis of 1,1-disubstituted hydrazines
Murakami,Yokoyama,Sasakura,Tamagawa
, p. 423 - 428 (2007/10/02)
1,1-disubstituted hydrazines were prepared from the corresponding 1,1-disubstituted ureas by means of the Hofmann rearrangement reaction. The yields were fairly good, except from the ureas susceptible to oxidation, and thus the present method represents an additional and efficient procedure for the synthesis of 1,1-disubstituted hydrazines.
