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Butyl fluoroformate, also known as butyl trifluoroacetate, is an organic compound with the chemical formula C6H11F3O2. It is a colorless liquid that is soluble in organic solvents and has a slight, fruity odor. This chemical is primarily used as a reagent in organic synthesis, particularly in the protection of alcohols and amines. It is also employed as a pesticide and as a component in the production of certain pharmaceuticals. Due to its reactivity and potential toxicity, butyl fluoroformate is handled with caution in laboratory settings.

2253-35-2

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2253-35-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2253-35-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,2,5 and 3 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 2253-35:
(6*2)+(5*2)+(4*5)+(3*3)+(2*3)+(1*5)=62
62 % 10 = 2
So 2253-35-2 is a valid CAS Registry Number.

2253-35-2Downstream Products

2253-35-2Relevant academic research and scientific papers

Direct Dehydroxytrifluoromethoxylation of Alcohols

Jiang, Xiaohuan,Deng, Zhijie,Tang, Pingping

, p. 292 - 295 (2018)

The first example of a direct dehydroxytrifluoromethoxylation of alcohols has been developed. This method generated an alkyl fluoroformate in situ from alcohols, followed by nucleophilic trifluoromethoxylation with trifluoromethyl arylsulfonate (TFMS) as the trifluoromethoxylation reagent. The reaction is operationally simple and scalable, and it proceeds under mild reaction conditions to provide access to a wide range of trifluoromethyl ethers from alcohols. In addition, this method is suitable for the late-stage trifluoromethoxylation of complex small molecules.

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