22545-15-9

Usage

Uses

2-(4-Ethoxyphenyl)ethanol, is used as a pharmaceutical intermediate.

InChI:InChI=1/C10H14O2/c1-2-12-10-5-3-9(4-6-10)7-8-11/h3-6,11H,2,7-8H2,1H3

Upstream product

• 41842-30-2 4-ethoxyphenylmagnesium bromide 
• 107-07-3 2-chloro-ethanol 
• 5459-40-5 4-ethoxystyrene 

Downstream Products

• 5459-40-5 4-ethoxystyrene 
• 85002-61-5 C₁₆H₁₇NO₄ 
• 74772-97-7 5-{4-[2-(4-Ethoxy-phenyl)-ethoxy]-benzyl}-thiazolidine-2,4-dione 
• 85003-18-5 2-Chloro-3-{4-[2-(4-ethoxy-phenyl)-ethoxy]-phenyl}-propionic acid methyl ester 

Relevant academic research and scientific papers

Highly sulphated cellulose: a versatile, reusable and selective desilylating agent for deprotection of alcoholic TBDMS ethers

A mild, efficient and rapid protocol was developed for the deprotection of alcoholic TBDMS ethers using a recyclable, eco-friendly highly sulphated cellulose sulphate acid catalyst in methanol. This acid catalyst selectively cleaves alcoholic TBDMS ethers in bis-TBDMS ethers containing both alcoholic and phenolic TBDMS ether moieties.

The scope of catalytic asymmetric hydroboration/oxidation with rhodium complexes of 1,1'-(2-diarylphosphino-1-naphthyl)isoquinolines

Preformed cationic Rh complexes of the title ligands are effective for the asymmetric hydroboration/oxidation of vinylarenes at ambient temperature. These vinylarenes may carry E- or Z-β substituents but not a substituents. Enantiomer excesses of up to 97% can be obtained in the most favourable cases. The enantioselectivity is moderately sensitive to the structure of the ligand: the difurylphosphino ligand gave superior results for electron-poor styrenes and the diphenylphosphino ligand the best results for electron-rich reactants. Mechanistic aspects are discussed.