22551-25-3

Basic information

• Product Name: 3-(methylsulfanyl)propanamide
• CAS NO: 22551-25-3
• Molecular Formula: C₄H₉NOS
• Molecular Weight: 119.1854
• Mol File: 22551-25-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 305.3°C at 760 mmHg
• Flash Point: 138.5°C
• Density: 1.09g/cm³
• Vapor Pressure: 0.000827mmHg at 25°C
• Refractive Index: 1.499
• CAS DataBase Reference: 3-(methylsulfanyl)propanamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(methylsulfanyl)propanamide(22551-25-3)
• EPA Substance Registry System: 3-(methylsulfanyl)propanamide(22551-25-3)

Safety Data

• Hazardous Substances Data: 22551-25-3(Hazardous Substances Data)

Upstream product

• 13532-18-8 methyl 3-(methylthio)propionate 

Relevant articles and documents

PYRIDAZINE DERIVATIVES AS RORC MODULATORS

Compounds of formula (I): (I) or pharmaceutical salts thereof, wherein m, n,, p, q A, B, Ri, R2, R3, R4, R5, R6and R7are as defined herein. Also disclosed are methods of making the compounds and using the compounds as RORs modulators for treatment of inflammatory diseases such as arthritis.

Synthesis and antiallergic activity of dimethyl-2- (phenylcarbamoyl)ethylsulfonium p-toluenesulfonate derivatives

The derivatives of dimethyl-2-(phenylcarbamoyl)ethylsulfonium p- toluenesulfonates were synthesized and evaluated for antiallergic activity. The 2,3-dihydroxyethoxy group was introduced to the phenyl ring from the standpoint of lipophilicity and electronic effects of substituent. The IgE- induced rat passive cutaneous anaphylaxis (PCA) was inhibited by oral administration of several substituted 2-[(4- propoxyphenyl)carbamoyl]ethyldimethylsulfonium p-toluenesulfonate derivatives. Among them (±)-2-[N-[4-(3-ethoxy-2- hydroxypropoxy)phenyl]carbamoyl]ethyldimethylsulfonium p-toluenesulfonate (1a, IPD-1151T) was found to possess considerable activity in the PCA test, and it was launched as Suplatast tosilate in Japan.