225641-94-1 Usage
Uses
Used in Pharmaceutical Industry:
3,4-Difluorophenylglycine is used as a key intermediate in the synthesis of pharmaceuticals for the treatment of neurological disorders. Its incorporation into drug molecules can enhance their bioavailability and metabolic stability, making it a promising candidate for drug development.
Used in Agrochemical Industry:
3,4-Difluorophenylglycine is utilized in the production of agrochemicals, such as pesticides and herbicides. Its unique chemical properties allow for the development of more effective and targeted agrochemicals, contributing to improved crop protection and yield.
Used in Specialty Chemicals Production:
3,4-Difluorophenylglycine serves as a building block in the synthesis of specialty chemicals, which have a wide range of applications in various industries, including materials science, coatings, and polymers. Its reactivity and properties enable the creation of novel compounds with specific characteristics, catering to the needs of different applications.
Check Digit Verification of cas no
The CAS Registry Mumber 225641-94-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,5,6,4 and 1 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 225641-94:
(8*2)+(7*2)+(6*5)+(5*6)+(4*4)+(3*1)+(2*9)+(1*4)=131
131 % 10 = 1
So 225641-94-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H7F2NO2/c9-5-2-1-4(3-6(5)10)7(11)8(12)13/h1-3,7H,11H2,(H,12,13)
225641-94-1Relevant academic research and scientific papers
Discovery of novel spiro-piperidine derivatives as highly potent and selective melanin-concentrating hormone 1 receptor antagonists
Suzuki, Takao,Moriya, Minoru,Sakamoto, Toshihiro,Suga, Takuya,Kishino, Hiroyuki,Takahashi, Hidekazu,Ishikawa, Makoto,Nagai, Keita,Imai, Yumiko,Sekino, Etsuko,Ito, Masahiko,Iwaasa, Hisashi,Ishihara, Akane,Tokita, Shigeru,Kanatani, Akio,Sato, Nagaaki,Fukami, Takehiro
scheme or table, p. 3072 - 3077 (2010/02/28)
Optimization of high-throughput screening hit 1a led to the identification of a novel spiro-piperidine class of melanin-concentrating hormone 1 receptor (MCH-1R) antagonists. Compound 3c was identified as a highly potent and selective MCH-1R antagonist, which has an IC50 value of 0.09 nM at hMCH-1R. The synthesis and structure-activity relationships of the novel spiro-piperidine MCH-1R antagonists are described.
